Evidence map›Paper›PMID 30811261›Full record

ArticleMolecular biology of the cell2019

Lymphatic endothelial cell calcium pulses are sensitive to spatial gradients in wall shear stress.

Vinay N Surya, Eleftheria Michalaki, Gerald G Fuller, Alexander R Dunn

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Response of lymphatic endothelial cells to combined spatial and temporal variations in fluid flow.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Vinay N SuryaDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.
Eleftheria MichalakiDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.
Gerald G FullerDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.
Alexander R DunnDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305.
Stanford University · USCardiovascular Institute of the South · US

Funding

Molecular mechanisms underlying flow sensing in lymphatic endothelial cellsR01HL128779 · NHLBI · STANFORD UNIVERSITY · PI DUNN, ALEXANDER R, FULLER, GERALD · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL128779
6 · The paper itself

Abstract

Cytosolic calcium (Ca

Indexed as

CalciumCalcium SignalingEndothelial CellsHumansHuman Umbilical Vein Endothelial CellsMechanotransduction, CellularMicrovesselsShear StrengthSignal TransductionStress, MechanicalCalcium

Identifiers

PMID30811261
PMCPMC6589782
OpenAlexW2916304514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.