Evidence map›Paper›PMID 30810976›Full record

Trial reportChinese journal of integrative medicine2019

Whether Fire-needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial.

Hu-Dan Pan, Xiao-Li Qi, Lei Wang, Jing-Yan He, Jiu-Li Liu, Yun-Bi Zhang, Ye Tian, Xing-Wu Duan, Hao-Yu Yang, Yan-Ping Bai

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Chinese journal of integrative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hu-Dan PanDepartment of Dermatology, China-Japan Friendship Hospital, Beijing, 100029, China.
Xiao-Li QiDepartment of Dermatology, China-Japan Friendship Hospital, Beijing, 100029, China.
Lei WangDepartment of Dermatology, China-Japan Friendship Hospital, Beijing, 100029, China.
Jing-Yan HeDepartment of Dermatology, Shunyi District Branch of Beijing Hospital of Traditional Chinese Medicine, Beijing, 101300, China.
Jiu-Li LiuDepartment of Dermatology, Shunyi District Branch of Beijing Hospital of Traditional Chinese Medicine, Beijing, 101300, China.
Yun-Bi ZhangDepartment of Dermatology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, 100700, China.
Ye TianDepartment of Dermatology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, 100700, China.
Xing-Wu DuanDepartment of Dermatology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, 100700, China.
Hao-Yu YangDepartment of Dermatology, Beijing Hospital of Traditional Chinese Medicine, Beijing, 100010, China.
Yan-Ping BaiDepartment of Dermatology, China-Japan Friendship Hospital, Beijing, 100029, China. zhi@tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe the clinical effectiveness and safety of fire-needle therapy, an external approach of Chinese medicine in treating plaque psoriasis.

methodsThis study was a two-parallel-arm randomized controlled trial. A total of 151 participants with plaque psoriasis were randomly assigned to the fire-needle therapy group (treatment group, 76 cases) or the control group (75 cases) at a 1:1 allocation ratio using SAS software. All participants received Oral Huoxue Jiedu Decoction (, HXJDD) and applied externally vaseline cream twice a day. Participants in the treatment group received fire-needle therapy once weekly for 4 weeks plus HXJDD and vaseline cream applied the same as the control group. The primary outcome measure was Psoriasis Area and Severity Index (PASI) score, and the secondary outcomes were Dermatology Life Quality Index (DLQL), and Hamilton Anxiety Rating Scale (HAMA), as well as Chinese medicine (CM) syndrome score and photos of target lesions. The indices were evaluated before and after treatment.

resultsSixty-eight patients in each group completed the study. The treatment group has not yet achieved significant improvement in PASI score (P>0.05) compared to the control group. However, significant differences were found between the two groups in relieving CM syndrome (P<0.05) and improving quality of life (P<0.05).

conclusionFire-needle appears to be safe and may have benefit for psoriasis, the short-term treatment and small sample size limit the conclusions of this study. Further rigorous randomized controlled trials with longer treatment are recommended.

Indexed as

Medicine, Chinese TraditionalAdultErythemaFemaleHumansMaleMiddle AgedPsoriasisQuality of LifeSeverity of Illness IndexChinese medicinefire-needle therapyHuoxue Jiedu Decoctionplaque psoriasisrandomized controlled trial

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.