ArticleBehavior genetics2019
A Genetic Investigation of the Well-Being Spectrum.
Article in Behavior genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Phenotypic and genetic analysis of a wellbeing factor score in the UK Biobank and the impact of childhood maltreatment and psychiatric illness.Translational psychiatry · 2022Pooled it
- The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.Biological psychiatry · 2020Pooled it
- Living happily ever after: longitudinal insights into enduring mental health and wellbeing.Social psychiatry and psychiatric epidemiology · 2026Article
- On the Association of Community Belonging With Over Time Changes in Self-Rated Health and Mental Health Since the COVID-19 Pandemic.The International journal of health planning and management · 2026Article
- Well-Being and Mental Health of Siblings of Children with Intellectual Disability: a Longitudinal Twin-Family Study.Journal of developmental and physical disabilities · 2026Article
- Child Wellbeing during the COVID-19 Pandemic: A Multi-cohort Comparison and a Multi-informant Genetic Study.Behavior genetics · 2025Article
- Relationships between wellbeing polygenic scores, brain structure, and psychopathology in children.medRxiv : the preprint server for health sciences · 2025Article
- Understanding the Relationship Between Ecological Momentary Assessment Methods, Sensed Behavior, and Responsiveness: Cross-Study Analysis.JMIR mHealth and uHealth · 2025Article
- The association between metabolite concentrations and wellbeing in adults.Scientific reports · 2025Article
- Genetic predisposition for negative affect predicts mental health burden during the COVID-19 pandemic.European archives of psychiatry and clinical neuroscience · 2025Article
- Polygenic risk of social isolation behavior and its influence on psychopathology and personality.Molecular psychiatry · 2024Article
- Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture.Translational psychiatry · 2024Article
- Connecting the dots: using a network approach to study the wellbeing spectrum.Current psychology (New Brunswick, N.J.) · 2024Article
- Building machine learning prediction models for well-being using predictors from the exposome and genome in a population cohort.Nature. Mental health · 2024Article
- Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2023Article
- Genetic factors explain a significant part of associations between adolescent well-being and the social environment.European child & adolescent psychiatry · 2022Article
- Self-rated health when population health is challenged by the COVID-19 pandemic; a longitudinal study.Social science & medicine (1982) · 2022Article
- The winding roads to adulthood: A twin study.JCPP advances · 2021Article
- Genetic underpinnings of sociability in the general population.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Genetic evidence for a large overlap and potential bidirectional causal effects between resilience and well-being.Neurobiology of stress · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
Abstract
The interrelations among well-being, neuroticism, and depression can be captured in a so-called well-being spectrum (3-phenotype well-being spectrum, 3-WBS). Several other human traits are likely linked to the 3-WBS. In the present study, we investigate how the 3-WBS can be expanded. First, we constructed polygenic risk scores for the 3-WBS and used this score to predict a series of traits that have been associated with well-being in the literature. We included information on loneliness, big five personality traits, self-rated health, and flourishing. The 3-WBS polygenic score predicted all the original 3-WBS traits and additionally loneliness, self-rated health, and extraversion (R
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.