ReviewBrazilian journal of cardiovascular surgery
Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting.
Review in Brazilian journal of cardiovascular surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- The effect of intraoperative dexmedetomidine on cognitive dysfunction after surgery: a updated meta-analysis.Journal of cardiothoracic surgery · 2021Pooled it
- Development and validation of a LASSO-derived prognostic model predicting postoperative cognitive dysfunction risk in off-pump coronary artery bypass grafting patients.Journal of thoracic disease · 2026Article
- Biomarkers of perioperative neurocognitive disorders after cardiac surgery: from mechanistic insights to clinical translation.Frontiers in neuroscience · 2026Review
- Predictive role of health literacy and e-health literacy on the self-care of patients undergoing CABG using open heart surgery.Journal of cardiothoracic surgery · 2025Article
- Effects of Dexamethasone on Cognitive Functions After Coronary Artery Bypass Grafting Surgery.Medicina (Kaunas, Lithuania) · 2025Article
- Assessment of Long-Term Mild and Major Neurocognitive Disorders 48 Months After Cardiac Surgery.International journal of geriatric psychiatry · 2025Article
- Jugular Venous Oxygen and Lactate Parameters for Predicting Early Cognitive Dysfunction after Off-Pump Coronary Artery Bypass Grafting: A Prospective Observational Study.Annals of Indian Academy of Neurology · 2025Article
- Nutritional Status and Post-Cardiac Surgery Outcomes: An Updated Review with Emphasis on Cognitive Function.Journal of clinical medicine · 2024Review
- Early postoperative neurocognitive complications in elderly patients: comparing those with and without preexisting mild cognitive impairment- a prospective study.BMC geriatrics · 2024Article
- Current perspectives on postoperative cognitive dysfunction in geriatric patients: insights from clinical practice.Frontiers in medicine · 2024Article
- CABG Patients Develop Global DNA Hypermethylation, That Negatively Affect the Mitochondrial Function and Promote Post-Surgical Cognitive Decline: A Proof of Concept in Small Cohort.Journal of clinical medicine · 2023Article
- Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction.Frontiers in medicine · 2023Review
- An Update on Postoperative Cognitive Dysfunction Following Cardiac Surgery.Frontiers in psychiatry · 2022Review
- Long-Term Neurophysiological Outcomes in Patients Undergoing Coronary Artery Bypass Grafting.Brazilian journal of cardiovascular surgery · 2021Article
- The relationship between aortic calcification on chest radiograph and neurocognitive impairment after coronary artery bypass grafting.Turk gogus kalp damar cerrahisi dergisi · 2021Article
- IS IT TIME TO REDEFINE COGNITIVE DYSFUNCTION AFTER CARDIAC SURGERY? THE IMPORTANCE OF METHODOLOGICAL CONSISTENCY.Acta clinica Croatica · 2021Review
- Beneficial Effects of a Short Course of Physical Prehabilitation on Neurophysiological Functioning and Neurovascular Biomarkers in Patients Undergoing Coronary Artery Bypass Grafting.Frontiers in aging neuroscience · 2021Article
- Neurofilament light: a narrative review on biomarker utility.Faculty reviews · 2021Review
- Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study.Medicina (Kaunas, Lithuania) · 2020Article
- Preoperative red cell distribution width predicts postoperative cognitive dysfunction after coronary artery bypass grafting.Bioscience reports · 2020Observational
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative cognitive dysfunction is a common complication following cardiac surgery. The incidence of cognitive dysfunction is more pronounced in patients receiving a cardiac operation than in those undergoing a non-cardiac operation. Clinical observations demonstrated that pulsatile flow was superior to nonpulsatile flow, and membrane oxygenator was superior to bubble oxygenator in terms of postoperative cognitive status. Nevertheless, cognitive assessments in patients receiving an on-pump and off-pump coronary artery bypass surgery have yielded inconsistent results. The exact mechanisms of postoperative cognitive dysfunction following coronary artery bypass grafting remain uncertain. The dual effects, neuroprotective and neurotoxic, of anesthetics should be thoroughly investigated. The diagnosis should be based on a comprehensive cognitive evaluation with neuropsychiatric tests, cerebral biomarker inspections, and electroencephalographic examination. The management strategies for cognitive dysfunction can be preventive or therapeutic. The preventive strategies of modifying surgical facilities and techniques can be effective for preventing the development of postoperative cognitive dysfunction. Investigational therapies may offer novel strategies of treatments. Anesthetic preconditioning might be helpful for the improvement of this dysfunction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.