Trial reportJournal of nutrition in gerontology and geriatrics
Influence of Weight Reduction and Enhanced Protein Intake on Biomarkers of Inflammation in Older Adults with Obesity.
Trial report in Journal of nutrition in gerontology and geriatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06157385 (The Effect of Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults), which is not on this map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults
Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Effect of host and gut microbiota-altering interventions on sarcopenia or its defining parameters: a systematic review and meta-analysis of nutrition-based intervention studies.Aging clinical and experimental research · 2025Pooled it
- Effects of dietary-based weight loss interventions on biomarkers of endothelial function: a systematic review and meta-analysis.European journal of clinical nutrition · 2023Pooled it
- Nutrition and Exercise Interventions to Improve Body Composition for Persons with Overweight or Obesity Near Retirement Age: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.Advances in nutrition (Bethesda, Md.) · 2023Pooled it
- Protein, Calcium, Vitamin D Intake and 25(OH)D Status in Normal Weight, Overweight, and Obese Older Adults: A Systematic Review and Meta-Analysis.Frontiers in nutrition · 2021Pooled it
- Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.Journal of the International Society of Sports Nutrition · 2026Trial
- Precision nutrition impact on metabolic health and quality of life in aging population after a 3-month intervention: A randomized intervention.The journal of nutrition, health & aging · 2024Trial
- Effect of Baseline BMI and IL-6 Subgroup Membership on Gait Speed Response to Caloric Restriction in Older Adults with Obesity.The journal of nutrition, health & aging · 2023Trial
- Influence of Protein Intake during Obesity Reduction on Physical Function and Body Habitus in Older Males with Prediabetes: A Pilot Study.Current developments in nutrition · 2026Article
- Metabolomic characterization of unintentional weight loss among community-dwelling older Black and White men and women.Aging cell · 2025Article
- Association of Body Mass Index and Clinical Outcomes in Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.Acta Cardiologica Sinica · 2025Article
- Review
- Effects of Physical Activity, VODiabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Protein Supplementation May Dampen Positive Effects of Exercise on Glucose Homeostasis: A Pilot Weight Loss Intervention.Nutrients · 2023Article
- Threshold effect and sex characteristics of the relationship between chronic inflammation and BMI.BMC endocrine disorders · 2023Article
- Type 2 Diabetes Mellitus, Non-Alcoholic Fatty Liver Disease, and Metabolic Repercussions: The Vicious Cycle and Its Interplay with Inflammation.International journal of molecular sciences · 2023Review
- The relation between C-reactive protein and serum amyloid A in patients with autoinflammatory diseases.Pediatric rheumatology online journal · 2022Article
- Effects of 2-Year Nutritional and Lifestyle Intervention on Oxidative and Inflammatory Statuses in Individuals of 55 Years of Age and over at High Cardiovascular Risk.Antioxidants (Basel, Switzerland) · 2022Article
- Weight loss and high-protein, high-fiber diet consumption impact blood metabolite profiles, body composition, voluntary physical activity, fecal microbiota, and fecal metabolites of adult dogs.Journal of animal science · 2022Article
- Comparison of Different Blood Transfusion Methods in Patients Undergoing Cesarean Section.Frontiers in surgery · 2022Article
- Impact of whey protein supplementation in a weight-loss intervention in rural dwelling adults: A feasibility study.Clinical nutrition ESPEN · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Both aging and obesity are associated with increased levels of pro-inflammatory metabolites, while weight reduction is associated with improvements in inflammatory status. However, few studies have explored the response of key inflammatory markers to the combined settings of weight reduction in an aging population. There are also few studies that have investigated the potential impact of diet composition on inflammatory marker responses. In the MEASUR-UP trial, we evaluated changes in baseline levels of inflammatory markers with post-study levels for a traditional weight loss control group versus a group with generous, balanced protein intake. In this 6-month randomized controlled trial (RCT), older (≥60 years) adults with obesity (BMI ≥30 kg/m
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.