SynthesisTechniques in coloproctology2019
Purse-string vs. linear skin closure at loop ileostomy reversal: a systematic review and meta-analysis.
Synthesis in Techniques in coloproctology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prevalence and risk factors of incisional hernia after ileostomy reversal: meta-analysis with meta-regression.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Circular (purse-string) vs primary skin closure following stoma closure: an up-to-date systematic review and meta-analysis.Techniques in coloproctology · 2025Pooled it
- The use of negative pressure wound therapy following stoma reversal: a systematic review and meta-analysis of randomized controlled trials.International journal of colorectal disease · 2025Pooled it
- Purse-string skin closure versus linear skin closure in people undergoing stoma reversal.The Cochrane database of systematic reviews · 2024Pooled it
- Impact of different skin suturing methods on patient prognosis after ileostomy closure.World journal of gastrointestinal surgery · 2025Trial
- Negative-pressure wound therapy after stoma reversal in colorectal surgery: a randomized controlled trial.BJS open · 2021Trial
- Ileostoma as a promising tool in pathophysiological study and clinical intervention: a review from bench to beside.Frontiers in immunology · 2026Review
- Incidence and Risk Factors for Incisional Hernia Following Ileostomy Takedown: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Current approach to loop ileostomy closure: a nationwide survey on behalf of the Italian Society of ColoRectal Surgery (SICCR).Updates in surgery · 2025Article
- Development of a novel nomogram for the prediction of surgical site infection risk after loop ileostomy closure.International journal of colorectal disease · 2024Article
- Observational
- Diverting ileostomy in benign colorectal surgery: the real clinical cost analysis.Updates in surgery · 2024Article
- Clinical impact of a multimodal pain management protocol for loop ileostomy reversal.Annals of coloproctology · 2024Article
- Clinical Benefits of Reducing Dead Space Using a Closed Suction Drain and Subcutaneous Large-bite Buried Suture Technique to Prevent Superficial Surgical-site Infections Following Primary Closure of a Diverting Stoma.Journal of the anus, rectum and colon · 2024Article
- Essential updates 2020/2021: Advancing precision medicine for comprehensive rectal cancer treatment.Annals of gastroenterological surgery · 2023Review
- A prospective study of 'circumferential purse-string approximation' vs. primary linear skin closure in stoma reversal.The Pan African medical journal · 2022Observational
- COMPARISON BETWEEN OSTOMY CLOSURE USING PURSE-STRING VERSUS LINEAR IN CHILDREN.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022Article
- A comparison of surgical site infections in children after stoma reversal between purse-string and linear closure.Pediatric surgery international · 2022Article
- A combination of subcuticular sutures and subcutaneous closed-suction drainage reduces the risk of incisional surgical site infection in loop ileostomy closure.Surgery today · 2021Article
- Comparison of Running Versus Interrupted Sutures for Fascial Closure in Ileostomy Takedown.Current health sciences journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is no level 1a evidence regarding the best technique for skin closure at loop ileostomy reversal. The aim of this study was to evaluate whether purse-string skin closure (PSC) is associated with lower surgical site infection (SSI) rates as compared to linear skin closure (LC).
methodsEMBASE, MEDLINE, Pubmed, Cochrane Library, Web of Science, and CINAHL databases were systematically searched. PSC was defined as a circumferential subcuticular suture leaving a small circular skin defect allowing for free drainage, granulation, and epithelialization. In LC, the wound edges were approximated side to side with or without drainage. The primary endpoint was SSI rate. Secondary endpoints included operating time, length of hospital stay, wound healing time, and incisional hernia rates. STUDY SELECTION: Inclusion criterion was any observational or experimental study comparing PSC to LC in patients undergoing ostomy reversal.
resultsTwenty studies (6 experimental and 14 observational) totaling 1812 patients (826 PSC and 986 LC) were included. SSI rates were significantly lower statistically and clinically in patients with PSC [OR (95% CI) = 0.14 (0.09, 0.21); p < 0.0001; NNT = 6] in the meta-analysis of all studies. The subgroup analysis of randomized trials [OR (95% CI) = 0.10 (0.04, 0.21); p < 0.0001; NNT = 6] as well as the analysis of randomized trials including patients with loop ileostomy only [OR (95% CI) = 0.12 (0.05, 0.28); p < 0.0001; NNT = 5] confirmed this finding.
conclusionsThis meta-analysis found that PSC was associated with significantly decreased rates of SSI in patients undergoing loop ileostomy reversal.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.