Evidence map›Paper›PMID 30809767›Full record

ArticleIndian journal of pediatrics2019

Risk Factors for Central Line-Associated Bloodstream Infection in Critically Ill Neonates.

Heladia García, Belina Romano-Carro, Guadalupe Miranda-Novales, Héctor Jaime González-Cabello, Juan Carlos Núñez-Enríquez

Abstract read
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In one paragraph

Article in Indian journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Heladia GarcíaAnalysis and Synthesis of Evidence Research Unit, National Medical Center, XXI Century, Mexican Social Security Institute, 330 Cuauhtémoc Avenue Col. Doctores. Municipality Cuauhtémoc, C.P., 06720, Mexico City, Mexico.
Belina Romano-CarroNeonatal Intensive Care Unit, Pediatric Hospital, National Medical Center, XXI Century, Mexican Social Security Institute, Mexico City, Mexico.
Guadalupe Miranda-NovalesAnalysis and Synthesis of Evidence Research Unit, National Medical Center, XXI Century, Mexican Social Security Institute, 330 Cuauhtémoc Avenue Col. Doctores. Municipality Cuauhtémoc, C.P., 06720, Mexico City, Mexico. guadalumiranda@outlook.es.ORCID http://orcid.org/0000-0003-3262-2608
Héctor Jaime González-CabelloNeonatal Intensive Care Unit, Pediatric Hospital, National Medical Center, XXI Century, Mexican Social Security Institute, Mexico City, Mexico.
Juan Carlos Núñez-EnríquezClinical Epidemiology Research Unit, Pediatric Hospital, National Medical Center, XXI Century, Mexican Social Security Institute, Mexico City, Mexico.
Mexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify independent risk factors to develop a central line- associated bloodstream infection (CLABSI) in critically ill neonates with major underlying diseases.

methodsA nested case-control study was conducted in a neonatal intensive care unit (NICU). Patients with a central venous catheter (CVC) were included. Cases were neonates who developed a CLABSI and controls were patients without CLABSI. Variables included: perinatal history, characteristics of the catheter, installation and catheter use, surgical interventions, and hospital stay. Odds ratio (OR) and 95% confidence intervals (CI) were calculated. X

resultsSeventy four cases and 105 controls were analyzed. Univariate risk factors were: any surgery, abdominal surgery, length of hospitalization (≥14 d), double-lumen CVC, surgical cut-down technique, complications, CVC placement in internal jugular vein, dressing type, blood transfusions, parenteral nutrition, and number of CVC manipulations (>200). In the logistic regression analysis, independent risk factors with a p value <0.05 were: double-lumen catheter (OR 5.8, 95% CI 1.2-30), length of hospitalization ≥14 d (OR 4.6, 95% CI 1.8-11.4), abdominal surgery (OR 2.7, 95% CI 1.2-6.2) and blood transfusions (OR 2.5, 95% CI 1.2-5.3).

conclusionsOne risk factor was related to the catheter itself. Management of underlying diseases in specialized NICU contributes to a greater extent to the development of a central line-associated bloodstream infection.

Indexed as

Birth WeightCase-Control StudiesCatheterization, Central VenousCatheter-Related InfectionsCongenital AbnormalitiesCritical IllnessFemaleGestational AgeHumansInfant, NewbornInfant, Newborn, DiseasesIntensive Care Units, NeonatalMaleRisk FactorsSex FactorsBloodstream infectionCentral line-associated infectionsCritically ill neonatesNosocomial infections

Identifiers

PMID30809767
OpenAlexW2917326793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.