ArticleSkeletal radiology2019
Aneurysmal bone cyst treated with percutaneous doxycycline: is a single treatment sufficient?
Article in Skeletal radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05521048 (Doxycycline Injection of Cutaneous Schwannoma in Neurofibromatosis Type 2), which is not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Doxycycline Injection of Cutaneous Schwannoma in Neurofibromatosis Type 2
Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Image-guided percutaneous interventions for bone tumors around the knee.Skeletal radiology · 2026Review
- Novel Clinical Practice Assessments: Informational Statements by the Musculoskeletal Tumor Society.Journal of surgical oncology · 2025Review
- A New Radiological Scoring System as a Method of Assessing Sclerotherapy Treatment Response for Aneurysmal Bone Cysts: A Retrospective Study.The Indian journal of radiology & imaging · 2024Article
- Efficacy of Percutaneous Treatment of Primary Aneurysmal Bone Cysts (ABCs): A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Single dose intralesional doxycycline foam infusion promotes bone growth and resolution of an odontoid aneurysmal bone cyst.Surgical neurology international · 2023Article
- Current strategies for the treatment of solitary and aneurysmal bone cysts: A review of the literature.Journal of bone oncology · 2021Review
- Primary Aneurysmal Bone Cyst and Its Recent Treatment Options: A Comparative Review of 74 Cases.Cancers · 2021Article
- Aneurysmal bone cyst in thoracolumbar spine.BJR case reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this case series is to report on the effectiveness of a single percutaneous injection of doxycycline as a primary treatment for aneurysmal bone cyst (ABC). MATERIALS AND
methodsA retrospective cohort study was conducted on seven patients diagnosed with ABC at various anatomical sites, with the intention to treat by a single percutaneous injection of doxycycline. Mean patient age was 14 years.
resultsSigns of treatment response were seen in six of seven patients after one injection. Three of the seven received a second treatment, despite signs of response. Another had expansion of the lesion after treatment, requiring excision. In total, three patients had a single injection of doxycycline as their sole treatment and another three showed signs of response after a single injection.
conclusionsA single percutaneous injection of doxycycline should be considered a viable primary treatment option for ABC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.