Evidence map›Paper›PMID 30809697›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2019

Positive pressure device treatment for Menière's disease: an overview of the current evidence and a meta-analysis.

Louise Devantier, Frank Liviu-Adelin Guldfred, Bjarki Ditlev Djurhuus, Mina Nicole Händel, Jesper Hvass Schmidt, Dan Dupont Hougaard, Henriette Edemann-Callesen

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Treatment of Menière's disease: a scoping review of the current evidence.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  2. Positive pressure therapy for Ménière's disease.The Cochrane database of systematic reviews · 2023
    Review
  3. Usefulness of Cochrane Reviews in Clinical Guideline Development-A Survey of 585 Recommendations.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Louise DevantierDepartment of Clinical Medicine, Aarhus University, Noerrebrogade 44, building 10G, 2nd floor, 8000, Aarhus C, Denmark. louisedevantier@clin.au.dk.ORCID http://orcid.org/0000-0001-7811-4874
Frank Liviu-Adelin GuldfredEar, Nose and Throat Clinic, Faxe, Denmark.
Bjarki Ditlev DjurhuusDepartment of Ear, Nose, Throat and Maxillofacial Surgery, Zealand University Hospital, Lykkebaekvej 1, 4600, Koege, Denmark.
Mina Nicole HändelThe Danish Health Authority, Islands Brygge 67, 2300, Copenhagen, Denmark.
Jesper Hvass SchmidtDepartment of ORL, Head and Neck Surgery and Audiology, Odense University Hospital, J. B. Winsløws Vej 4, 5000, Odense C, Denmark.
Dan Dupont HougaardDepartment of Otolaryngology, Head & Neck Surgery and Audiology, Aalborg University Hospital, Havrevangen 1, 9000, Aalborg, Denmark.
Henriette Edemann-CallesenThe Danish Health Authority, Islands Brygge 67, 2300, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective was to critically assess the current evidence investigating the efficacy of using a positive pressure device in patients with definite or probable Menière's disease.

methodsWe performed a systematic literature search in MEDLINE, EMBASE and PsycINFO up to February 2018. We included both systematic reviews and primary literature [randomized controlled trials (RCTs)] investigating positive pressure treatment, in patients (≥ 18 years of age), with Menière's disease. We assessed the internal validity of systematic reviews using the AMSTAR tool and risk of bias of primary studies using the Cochrane Risk of bias tool. We performed a meta-analysis for each outcome based on the identified studies. The overall certainty of evidence for the outcomes was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE).

resultsThe search for systematic reviews identified four relevant reviews. These all included the same four RCTs. An updated search identified one additional RCT. In total, five RCTs were included in the data synthesis. Our data synthesis showed no effect of positive pressure treatment on primary nor secondary outcomes. No serious adverse events were reported. The overall certainty of evidence ranged from very low to low, due to the serious risk of bias and imprecision.

conclusionThe current available evidence does not support positive pressure device treatment in patients with Menière's disease. However, the limitations of the current literature hinder the possibility of any solid conclusion. There remains a need for randomized controlled trials of high quality to fully access the utility of this treatment.

Indexed as

PressureBiasHumansMeniere DiseaseSystematic Reviews as TopicLow-pressure deviceMeniere’s diseaseMeniett devicePositive pressure therapyVertigo

Identifiers

PMID30809697

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.