Evidence map›Paper›PMID 30809577›Full record

ArticleInternational journal of women's dermatology2019

New oral and topical approaches for the treatment of melasma.

P E Grimes, S Ijaz, R Nashawati, D Kwak

Open access · goldAbstract read
In one paragraph

Article in International journal of women's dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 121 citations in OpenAlex.

  1. Article
  2. Global consensus on the management of melanin hyperpigmentation disorders.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Latin American consensus on the treatment of melasma.International journal of dermatology · 2025
    Review
  8. Article
  9. Uses of tranexamic acid and the risk of thrombosis in women: Number 11 - 2025.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Carotenoids in red fruit (Biomedical reports · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Clinical Applications ofLife (Basel, Switzerland) · 2023
    Review
  18. Review
  19. Skin Pigmentation Types, Causes and Treatment-A Review.Molecules (Basel, Switzerland) · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

P E GrimesVitiligo & Pigmentation Institute of Southern California, Los Angeles, California.
S IjazVitiligo & Pigmentation Institute of Southern California, Los Angeles, California.
R NashawatiVitiligo & Pigmentation Institute of Southern California, Los Angeles, California.
D KwakVitiligo & Pigmentation Institute of Southern California, Los Angeles, California.
Vitiligo and Pigmentation Institute of Southern California · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melasma is a common, therapeutically challenging, and universally relapsing disorder of hyperpigmentation that is most often observed in women and individuals with Fitzpatrick Skin Types III through VI. The pathogenesis of melasma is complex and protean. Contributing factors that are often implicated in the etiopathogenesis of this condition include a genetic predisposition, intense ultraviolet radiation exposure, and hormonal influences. Therapeutic interventions for melasma include a multimodality approach incorporating photoprotection agents, topical and oral skin lighteners, and resurfacing procedures. Given our expanding knowledge of the pathogenesis of melasma, new and effective treatments are expanding our therapeutic armamentarium. This article reviews new and emerging oral and topical treatments for melasma.

Indexed as

lightening agentsMelasmanew and emergingoral treatmentsphotoprotectiontopical treatments

Identifiers

PMID30809577
PMCPMC6374710
OpenAlexW2900919730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.