ArticleInternational journal of ophthalmology2019
The Alexandria retinopathy of prematurity model (Alex-ROP): postnatal weight gain screening algorithm application in a developing country.
Article in International journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Validation of DIGIROP models and decision support tool for prediction of treatment for retinopathy of prematurity on a contemporary Swedish cohort.The British journal of ophthalmology · 2023Article
- Retrospective validation of G-ROP, CO-ROP, Alex-ROP, and ROPscore predictive algorithms in two Chinese medical centers.Frontiers in pediatrics · 2023Article
- Jeddah Retinopathy of Prematurity (JED-ROP) Screening Algorithm.Global pediatric health · 2023Article
- Development and validation of a new clinical decision support tool to optimize screening for retinopathy of prematurity.The British journal of ophthalmology · 2022Article
- Commentary: Predicting need for treatment in retinopathy of prematurity - The elusive Holy Grail.Indian journal of ophthalmology · 2022Article
- Different retinopathy of prematurity severity and outcomes in triplets: A case report.SAGE open medical case reports · 2020Article
- Incidence, risk factors, progression, and involution in retinopathy of prematurity at a tertiary care center in South India.Oman journal of ophthalmologyArticle
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Authors and funding
2 authors.
Funding
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Abstract
aimTo suggest a novel retinopathy of prematurity (ROP) screening model in developing countries incorporating postnatal weight gain ratios (PWGR) to traditional parameters to maintain sensitivity and improve specificity in detecting ROP.
methodsAnalysis of weekly PWGR of infants from one tertiary referral center during six months to determine the age at which the PWGR with the highest predictability for ROP development which was referred to as the postnatal net weight gain ratio (NWGR). NWGR was added to conventional criteria to describe a new model (The Alex-ROP model).
resultsOf 560 infants were included. NWGR 28d after birth was the most predictive factor for the development of ROP. A new model Alex-ROP recommending screening infants with gestational age (GA) ≤33wk or birth weight ≤1500 g and NWGR at 28d after birth <0.3 was suggested. A second screening model referred to as High-grade Alex-ROP (Hg Alex-ROP) model to detect worse grade ROP (Both type 1 and type 2) recommending a cutoff point of NWGR <0.15 between birth and 28
conclusionBoth Alex-ROP and Hg Alex-ROP models are easy to apply to improve the specificity of ROP screening in developing countries while maintaining high sensitivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.