Evidence map›Paper›PMID 30809481›Full record

ArticleInternational journal of ophthalmology2019

Intravitreal conbercept injection for neovascular age-related macular degeneration.

Bing-Hui Wu, Bing Wang, Hui-Qin Wu, Qin Chang, Hui-Qin Lu

Abstract read
In one paragraph

Article in International journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Therapeutic potential of iron chelators in retinal vascular diseases.International journal of ophthalmology · 2023
    Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bing-Hui WuDepartment of Ophthalmology, Xi'an No.1 Hospital, Xi'an 710001, Shaanxi Province, China.
Bing WangDepartment of Ophthalmology, Xi'an No.1 Hospital, Xi'an 710001, Shaanxi Province, China.
Hui-Qin WuDepartment of Ophthalmology, Xi'an No.1 Hospital, Xi'an 710001, Shaanxi Province, China.
Qin ChangDepartment of Ophthalmology, Xi'an No.1 Hospital, Xi'an 710001, Shaanxi Province, China.
Hui-Qin LuDepartment of Ophthalmology, Xi'an No.1 Hospital, Xi'an 710001, Shaanxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the efficacy and safety of intravitreal injection of conbercept in patients with neovascular age-related macular degeneration (AMD).

methodsRetrospective review of 66 eyes of 63 patients with neovascular AMD. All patients received 0.5 mg intravitreal injections of conbercept monthly for 3 consecutive months, and then

resultsThe mean BCVA and CMT of 66 eyes (63 patients) were 1.11±0.60, 533.20±219.95 µm at baseline, and were 0.68±0.38, 310.28±125.60 µm at 3mo. No subjects were lost during the first three months, the improvements were all significantly (

conclusionIntravitreal injection of conbercept appears to significantly improve visual acuity and anatomical outcomes in patients with neovascular AMD, no serious adverse reactions and complications are observed.

Indexed as

age-related macular degenerationconberceptintravitreal injection

Identifiers

PMID30809481
PMCPMC6376238

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.