Evidence map›Paper›PMID 30809478›Full record

ArticleInternational journal of ophthalmology2019

Effect of subconjunctival injection with conbercept as an adjuvant to filtration surgery for open angle glaucoma: a prospective randomized interventional 6-month follow-up study.

Jing Zhang, Vikash Vikash, Ping Wang, Tian Zheng, Dong-Lai Chen, Qing Wang, Min Ke

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Animal models of scarring control.Eye (London, England) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jing ZhangDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China.
Vikash VikashDepartment of Gastroenterology and Pathology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Ping WangDepartment of Ophthalmology, Wuhan Third Hospital-Tongren Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Tian ZhengDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China.
Dong-Lai ChenDepartment of Ophthalmology, the Second People's Hospital of Honghu, Honghu 433202, Hubei Province, China.
Qing WangDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China.
Min KeDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China.
Wuhan University · CNZhongnan Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare the safety and efficacy of subconjunctival injection with conbercept and 5-fluorouracil (5-FU) for open angle glaucoma (OAG) patients after filtration surgery.

methodsAs a prospective randomized interventional trial, 36 eyes from 36 patients after OAG surgery were collected and divided randomly into conbercept and 5-FU groups. All patients were subconjunctivally injected with either conbercept (0.2 mL) or 5-FU (0.2 mL) on the 5

resultsThere were significant differences in IOP between the conbercept and 5-FU groups 1mo (conbercept group: 12.17±1.04 mm Hg; 5-FU group: 13.50±2.33 mm Hg,

conclusionSubconjunctival injection of conbercept has a safe, effective, and tolerable profile for open angle glaucoma patients with distinct conjunctival congestion after filtration surgery.

Indexed as

5-fluorouracilconberceptfiltration surgeryopen angle glaucoma

Identifiers

PMID30809478
PMCPMC6376237
OpenAlexW2992431870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.