Evidence map›Paper›PMID 30809446›Full record

ArticlePeerJ2019

Comparative study on the composition of four different varieties of garlic.

Cun Chen, Jing Cai, Song-Qing Liu, Guo-Liang Qiu, Xiao-Gang Wu, Wei Zhang, Cheng Chen, Wei-Liang Qi, Yong Wu, Zhi-Bin Liu

Abstract read
In one paragraph

Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Potential use of garlic products in ruminant feeding: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023
    Review
  3. Phytochemical Profiling ofPlants (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cun ChenCollege of Chemistry and Life Science, Chengdu Normal University, Chengdu, PR China.
Jing CaiWest China School of Pharmacy, Sichuan University, Chengdu, PR China.
Song-Qing LiuCollege of Chemistry and Life Science, Chengdu Normal University, Chengdu, PR China.
Guo-Liang QiuKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, PR China.
Xiao-Gang WuChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, PR China.
Wei ZhangCollege of Bioengineering, Sichuan University of Science and Engineering, Zigong, PR China.
Cheng ChenCollege of Chemistry and Life Science, Chengdu Normal University, Chengdu, PR China.
Wei-Liang QiCollege of Chemistry and Life Science, Chengdu Normal University, Chengdu, PR China.
Yong WuCollege of Chemistry and Life Science, Chengdu Normal University, Chengdu, PR China.
Zhi-Bin LiuKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Garlic is used as a medicinal seasoning worldwide. The aim of this work was to compare four varieties of garlic: 'Taicangbaipi', 'Ershuizao', 'Hongqixing', and 'Single-clove'; among them, 'Ershuizao' and 'Hongqixing' are unique to the Sichuan Province of China. Firstly, soluble sugar, starch, and the protein content of the garlic were analysed. There was more soluble sugar in 'Single-clove', total starch in 'Hongqixing', and protein content in 'Ershuizao' relative to the other three varieties, respectively. Gas chromatography-mass spectrometry analysis showed that 'Ershuizao' and 'Hongqixing' contained high levels of 5-hydroxymethylfurfural, which has antitumor, antioxidant, and cytoprotective effects. Indeed, the extracts from these two types of garlic were more effective at inhibiting tumour growth than that from the others. Moreover, the sulphide content and antimicrobial effects of 'Ershuizao' and 'Hongqixing' garlic were also higher than those of the other two types of garlic. In addition, changes observed in the membrane permeability and protein leakage suggest that the antimicrobial activity of the 'Ershuizao' and 'Hongqixing' extracts may be due to the destruction of the structural integrity of the cell membranes, leading to cell death.

Indexed as

5-HydroxymethylfurfuralAntimicrobial effectsAntitumorGarlicGC–MSNutrition analysis

Identifiers

PMID30809446
PMCPMC6387757

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.