Evidence map›Paper›PMID 30809393›Full record

ArticleJournal of advanced research2019

Reversal of carbapenem-resistance in

Zong-Yen Wu, Yao-Ting Huang, Wen-Cheng Chao, Shu-Peng Ho, Jan-Fang Cheng, Po-Yu Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. The extended mobility of plasmids.Nucleic acids research · 2025
    Review
  6. Frontiers in medicine · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Engineering probioticApplied and environmental microbiology · 2024
    Article
  11. Review
  12. Characterization of CRISPR-Cas Systems inPathogens (Basel, Switzerland) · 2024
    Article
  13. CRISPR-Cas System: A New Dawn to Combat Antibiotic Resistance.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Zong-Yen WuUS Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.
Yao-Ting HuangDepartment of Computer Science and Information Engineering, National Chung Cheng University, Chia-Yi, Taiwan.
Wen-Cheng ChaoDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Shu-Peng HoDepartment of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Jan-Fang ChengUS Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.
Po-Yu LiuDivision of Infectious Diseases, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
National Chung Hsing University · TWJoint Genome Institute · USNational Chung Cheng University · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance in pathogens is a growing threat to human health. Of particular concern is resistance to carbapenem, which is an antimicrobial agent listed as critically important by the World Health Organization. With the global spread of carbapenem-resistant organisms, there is an urgent need for new treatment options.

Indexed as

Beta-lactamase OXA-55CarbapenemCas9, CRISPR-associated protein 9COGs, Clusters of Orthologous Groups of proteinsCRISPR-Cas9CRISPR, clustered regularly interspaced short palindromic repeatDAP, diaminopimelic acidNCBI, National Center for Biotechnology InformationPGAAP, Prokaryotic Genomes Automatic Annotation PipelineResistanceShewanella algaeSMRT, single-molecule real-time

Identifiers

PMID30809393
PMCPMC6374997
OpenAlexW2914775462

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.