ReviewMultidisciplinary respiratory medicine2019
Obstructive sleep apnea and comorbidities: a dangerous liaison.
Review in Multidisciplinary respiratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
154 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Multi-ancestry investigation of the genomics of erectile dysfunction.Nature communications · 2025Pooled it
- Nutritional status in non-cancer older adults experiencing dry mouth -meta-analysis and systematic review.Journal of dentistry · 2025Pooled it
- Effectiveness of continuous positive airway pressure therapy on romantic relationships and intimacy among individuals with obstructive sleep apnea: A systematic review and a meta-analysis.Journal of sleep research · 2025Pooled it
- Pooled it
- The association between obstructive sleep apnoea and wound healing: a systematic review.Sleep & breathing = Schlaf & Atmung · 2023Pooled it
- Validation of the STOP questionnaire as a screening tool for OSA among different populations: a systematic review and meta-regression analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Pooled it
- Prevalence of type 2 diabetes in psychiatric disorders: an umbrella review with meta-analysis of 245 observational studies from 32 systematic reviews.Diabetologia · 2022Pooled it
- Association between obstructive sleep apnea and health-related quality of life in untreated adults: a systematic review.Sleep & breathing = Schlaf & Atmung · 2021Pooled it
- Sudden death in individuals with obstructive sleep apnoea: a systematic review and meta-analysis.BMJ open respiratory research · 2021Pooled it
- Clinical safety and hemodynamic, cardiac autonomic and inflammatory responses to a single session of inspiratory muscle training in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2022Trial
- Implementation of a digital obstructive sleep apnoea pathway in a tertiary respiratory service: a prospective service evaluation.Sleep medicine: X · 2026Article
- The diagnostic yield of a structured comorbidity workup in a real-life outpatient population with obstructive sleep apnea: a cross-sectional study.Annals of medicine · 2026Observational
- Investigating the Incremental Cost and Utilization Burden of Obstructive Sleep Apnea in Overweight to Severely Obese Patients.Diabetes, obesity & metabolism · 2026Article
- Toward improved screening models for obstructive sleep apnea: comments on the conceptual framework by Molnár et al.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Association of Metabolic Score for Insulin Resistance With Resistant Hypertension and Hypertension in Obstructive Sleep Apnea.The clinical respiratory journal · 2026Article
- From retrospective to prospective design: a short communication on why the methodological paradigm for qualitative research on delayed medical consultation in obstructive sleep apnea may need to be reconstructed.Sleep & breathing = Schlaf & Atmung · 2026Review
- The South Texas Oral Health Network Study of Practitioners' Approaches to Oral Appliance Therapy Titration for Obstructive Sleep Apnea and Their Impact on Patient Outcomes (PAOSA): Protocol for a Prospective Observational Study.JMIR research protocols · 2026Article
- Relationship between sleep duration and sleep quality with hypertension in community dwelling adults: Ardakan Cohort Study on Ageing (ACSA).Journal of health, population, and nutrition · 2026Article
- Clinical Insights Regarding Oral Health Among Untreated and Positive Airway Pressure Treated Obstructive Sleep Apnea Patients.Journal of sleep research · 2026Article
- Is obstructive sleep apnea a driver of cancer and chronic disease risk? A real-world analysis of over 3 million patients.BMC pulmonary medicine · 2026Article
94 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged recently, and new conditions significantly associated with OSA are increasingly reported. A high comorbidity burden worsens prognosis, but some data suggest that CPAP might be protective especially in patients with comorbidities. Aim of this narrative review is to provide an update on recent studies, with special attention to cardiovascular and cerebrovascular comorbidities, the metabolic syndrome and type 2 diabetes, asthma, COPD and cancer. Better phenotypic characterization of OSA patients, including comorbidities, will help to provide better individualized care. The unsatisfactory adherence to CPAP in patients without daytime sleepiness should prompt clinicians to examine the overall risk profile of each patient in order to identify subjects at high risk for worse prognosis and provide the optimal treatment not only for OSA, but also for comorbidities.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.