Evidence map›Paper›PMID 30809315›Full record

ArticleTheranostics2019

Nanoparticle Binding to Urokinase Receptor on Cancer Cell Surface Triggers Nanoparticle Disintegration and Cargo Release.

Shijie Li, Cai Yuan, Jincan Chen, Dan Chen, Zhuo Chen, Wenlie Chen, Shufeng Yan, Ping Hu, Jinping Xue, Rui Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. CNN-based glioma detection in MRI: A deep learning approach.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  3. Article
  4. Review
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  8. Article
  9. Review
  10. Therapeutics targeting the fibrinolytic system.Experimental & molecular medicine · 2020
    Review
  11. Nanoparticle Drug Delivery Systems for α-Mangostin.Nanotechnology, science and applications · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Shijie LiFuzhou University, Fuzhou, Fujian 350116, China.
Cai YuanFuzhou University, Fuzhou, Fujian 350116, China.
Jincan ChenState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Dan ChenFuzhou University, Fuzhou, Fujian 350116, China.
Zhuo ChenState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Wenlie ChenFujian Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Shufeng YanState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Ping HuState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Jinping XueFuzhou University, Fuzhou, Fujian 350116, China.
Rui LiState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Ke ZhengFuzhou University, Fuzhou, Fujian 350116, China.
Mingdong HuangFuzhou University, Fuzhou, Fujian 350116, China.
Fujian Institute of Research on the Structure of Matter · CNChinese Academy of Sciences · CNFujian University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cell expresses abundant surface receptors. These receptors are important targets for cancer treatment and imaging applications. Our goal here is to develop nanoparticles with cargo loading and tumor targeting capability.

Indexed as

AnimalsCarcinoma, HepatocellularCell Line, TumorDisease Models, AnimalDrug CarriersHumansMiceMolecular Targeted TherapyNanoparticlesNeoplasm TransplantationPhotochemotherapyPhotosensitizing AgentsProtein BindingReceptors, Urokinase Plasminogen ActivatorRecombinant Fusion ProteinsTransplantation, HeterologousDrug CarriersPhotosensitizing AgentsReceptors, Urokinase Plasminogen ActivatorRecombinant Fusion Proteinsamino terminal fragment of urokinase-type plasminogen activatorcargo releasehuman serum albuminreceptor-triggered disintegrationurokinase receptor

Identifiers

PMID30809315
PMCPMC6376475
OpenAlexW2914806940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.