Evidence map›Paper›PMID 30809308›Full record

ArticleTheranostics2019

Targeted Drug Delivery and Image-Guided Therapy of Heterogeneous Ovarian Cancer Using HER2-Targeted Theranostic Nanoparticles.

Minati Satpathy, Liya Wang, Rafal J Zielinski, Weiping Qian, Y Andrew Wang, Aaron M Mohs, Brad A Kairdolf, Xin Ji, Jacek Capala, Malgorzata Lipowska and 3 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 112 citations in OpenAlex.

  1. Review
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  6. Designing the Next Generation of Biomaterials through Nanoengineering.Advanced materials (Deerfield Beach, Fla.) · 2025
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  20. New trends in diagnosing and treating ovarian cancer using nanotechnology.Frontiers in bioengineering and biotechnology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Minati SatpathyDepartments of Surgery, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Liya WangDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Rafal J ZielinskiDepartment of Experimental Therapeutics, University of Texas, MD Anderson Cancer Center, Houston, TX, 77030, USA.
Weiping QianDepartments of Surgery, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Y Andrew WangOcean NanoTech, LLC, San Diego, CA, 92126, USA.
Aaron M MohsDepartment of Biomedical Engineering, Emory University, Atlanta, GA, 30322, USA.
Brad A KairdolfDepartment of Biomedical Engineering, Emory University, Atlanta, GA, 30322, USA.
Xin JiOcean NanoTech, LLC, San Diego, CA, 92126, USA.
Jacek CapalaClinical Radiation Oncology Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Malgorzata LipowskaDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Shuming NieDepartment of Biomedical Engineering, Emory University, Atlanta, GA, 30322, USA.
Hui MaoDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Lily YangDepartments of Surgery, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Emory University · USOcean NanoTech (United States) · USThe University of Texas MD Anderson Cancer Center · US

Funding

Contrast-Enhanced and Image-Guided Surgery of Lung CancerR01CA163256 · NCI · EMORY UNIVERSITY · PI JO, HANJOONG, SINGHAL, SUNIL · 2011 to 2015
$6.5M
Stroma Breaking Theranostic Nanoparticle for Targeted Pancreatic Cancer TherapyU01CA198913 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2015 to 2019
$3.0M
Targeted therapy of peritoneal carcinomatosis using theranostic nanoparticlesR01CA202846 · NCI · EMORY UNIVERSITY · PI MAO, HUI, WANG, YONGQIANG ANDREW · 2016 to 2020
$2.4M
Theranostic Nano particles for Targeted Treatment of Pancreatic CancerU01CA151810 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2010 to 2014
$2.2M
MRI Capable Receptor Targeted Drug Delivery for Pancreatic CancerR01CA154846 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2011 to 2015
$2.1M
Targeted Therapy of Triple Negative Breast Cancer Using Theranostic NanoparticlesR01CA154129 · NCI · EMORY UNIVERSITY · PI YANG, LILY · 2011 to 2015
$1.7M
Targeted Nanoprobes For Intraoperative optical Imaging of Breast Cancer MarginsR01CA133722 · NCI · EMORY UNIVERSITY · PI YANG, LILY · 2008 to 2012
$1.6M
NCI NIH HHS R01 CA133722NCI NIH HHS R01 CA154129NCI NIH HHS R01 CA154846NCI NIH HHS R01 CA163256NCI NIH HHS R01 CA202846NCI NIH HHS U01 CA151810NCI NIH HHS U01 CA198913
6 · The paper itself

Abstract

Cancer heterogeneity and drug resistance limit the efficacy of cancer therapy. To address this issue, we have developed an integrated treatment protocol for effective treatment of heterogeneous ovarian cancer.

Indexed as

Drug Delivery SystemsMagnetic Resonance Imaging, InterventionalAnimalsAntineoplastic AgentsCell Line, TumorCisplatinErb-b2 Receptor Tyrosine KinasesFeasibility StudiesFemaleFerric CompoundsHumansMetal NanoparticlesMice, NudeOvarian NeoplasmsTheranostic NanomedicineXenograft Model Antitumor AssaysAntineoplastic AgentsCisplatinERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesFerric Compoundsferric oxideMR image-guided cancer therapyresistant mechanismspectroscopic imagingtargeted drug deliverytheranostic nanoparticles

Identifiers

PMID30809308
PMCPMC6376473
OpenAlexW2911411908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.