ReviewWorld journal of gastroenterology2019
Solutions for submucosal injection: What to choose and how to do it.
Review in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
EndoscoPic Submucosal dIssection Using geL Versus glycerOl for Submucosal iNjection: a Randomized Controlled Multicentric Trial (EPSILON)
Usage of Tranexamic Acid During Colonic Endoscopic Resection Procedures for Reduction Intraprocedural and Postprocedural Bleeding
Comparison Between Epinephrine Versus Tranexamic Acid Usage During Upper Gastrointestinal Tract Endoscopic Resection Procedures for the Reduction of Intraprocedural and Postprocedural Bleeding
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Wound infection prevention strategies in colorectal endoscopic mucosal resection: A meta-analysis of prophylactic measures.International wound journal · 2024Pooled it
- Review on colorectal endoscopic submucosal dissection focusing on the technical aspect.Surgical endoscopy · 2020Pooled it
- SAFETY AND EFFECTIVENESS OF BLUE EYE HYPERTONIC SOLUTION VERSUS SALINE SOLUTION IN THE TREATMENT OF FLAT COLONIC LESIONS: A RANDOMIZED CLINICAL TRIAL.Arquivos de gastroenterologia · 2026Trial
- Randomized controlled trial investigating use of submucosal injection of EverLift™ in rates of complete resection of non-pedunculated 4-9 mm polyps.International journal of colorectal disease · 2022Trial
- Application of Hemocoagulase Bothrops Atrox in the submucosal injection for endoscopic submucosal dissection: a preliminary trial.European journal of gastroenterology & hepatology · 2021Trial
- Submucosal injection-related foreign body reaction complicating endoscopic submucosal dissection: this time, it is not the usual suspect.iGIE : innovation, investigation and insights · 2026Article
- Sodium Alginate-Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection.Advanced healthcare materials · 2026Article
- Dye-free versus dye-containing submucosal injection solutions in ESD for colorectal LST: a multi-center retrospective study on efficacy and safety.Surgical endoscopy · 2026Article
- Tranexamic Acid Versus Epinephrine as Submucosal Injectate During Endoscopic Mucosal Resection of Large Colorectal Lesions: A Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Endoscopic Delivery of Hydrogels: A Novel Strategy for Treating Early-Stage Gastrointestinal Tumors.Bioengineering (Basel, Switzerland) · 2026Review
- Use of rebamipide solution as a submucosal injection material to prevent esophageal stricture after endoscopic submucosal dissection: Animal study.Endoscopy international open · 2026Article
- Article
- Magnetic hydrogel-assisted endoscopic submucosal dissection of large intestine in vitro animal experimental study.Techniques in coloproctology · 2025Article
- Review of the role of submucosal injection materials in digestive endoscopy.Annals of medicine · 2025Review
- Advancements in injection materials for submucosal lifting in endoscopic interventions.World journal of gastrointestinal surgery · 2025Review
- Impact of saline fluid cushion on thermal damage during the double-flap technique after proximal gastrectomy using porcine stomach.Scientific reports · 2025Article
- Unsuspected efficacy of starch-based polysaccharideWorld journal of gastrointestinal endoscopy · 2025Article
- Endoscopic Management of Ampullary Adenomas: A Comprehensive Review.Journal of clinical medicine · 2025Review
- A novel self-assembling peptide as new submucosal injection solution in endoscopic submucosal dissection.Surgical endoscopy · 2025Article
- Risk Factors for Perforation in Endoscopic Treatment for Early Colorectal Cancer: A Nationwide ENTER-K Study.Gut and liver · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the past decades, endoscopic resection techniques have gradually improved and gained more importance for the management of premalignant lesions and early cancers. These endoscopic resection techniques can be divided in 3 major groups: snare polipectomy, endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD). The use of submucosal injection is essential for the majority of EMR techniques and is an integral part of ESD, whereas during polipectomy it is not crucial in most cases except to prevent bleeding in large polyps and/or those with large stalks as an alternative to mechanical methods. Injection provides a lifting up effect of the lesion separating it from the muscular layer, thereby reducing thermal injury and the risk of perforation and bleeding while also facilitating
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.