Evidence map›Paper›PMID 30808766›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Tyramine action on motoneuron excitability and adaptable tyramine/octopamine ratios adjust

Natalie Schützler, Chantal Girwert, Isabell Hügli, Giriram Mohana, Jean-Yves Roignant, Stefanie Ryglewski, Carsten Duch

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Selective octopaminergic tuning of mushroom body circuits during memory formation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Octopamine receptors inFrontiers in molecular neuroscience · 2026
    Article
  7. Hunger Recruits a Parallel Circuit Encoding Alcohol Reward.bioRxiv : the preprint server for biology · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Octopamine in the mushroom body circuitry for learning and memory.Learning & memory (Cold Spring Harbor, N.Y.) · 2024
    Review
  12. Article
  13. Effect ofFrontiers in pharmacology · 2024
    Article
  14. Tyramine and itseLife · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Natalie SchützlerInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, 55099 Mainz, Germany.
Chantal GirwertInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, 55099 Mainz, Germany.
Isabell HügliInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, 55099 Mainz, Germany.
Giriram MohanaInstitute of Molecular Biology, Johannes Gutenberg University Mainz, 55099 Mainz, Germany.
Jean-Yves RoignantInstitute of Molecular Biology, Johannes Gutenberg University Mainz, 55099 Mainz, Germany.
Stefanie RyglewskiInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, 55099 Mainz, Germany; ryglewsk@uni-mainz.de cduch@uni-mainz.de.
Carsten DuchInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, 55099 Mainz, Germany; ryglewsk@uni-mainz.de cduch@uni-mainz.de.
Johannes Gutenberg University Mainz · DEInstitute of Molecular Biology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenergic signaling profoundly modulates animal behavior. For example, the invertebrate counterpart of norepinephrine, octopamine, and its biological precursor and functional antagonist, tyramine, adjust motor behavior to different nutritional states. In

Indexed as

AnimalsBehavior, AnimalCalcium Channels, L-TypeDrosophila melanogasterFood DeprivationLarvaLocomotionMixed Function OxygenasesMotor NeuronsNutritional StatusOctopamineReceptors, Biogenic AmineSynapsesTyramineCalcium Channels, L-TypeMixed Function OxygenasesOctopamineReceptors, Biogenic AmineTyraminetyramine beta-hydroxylasetyramine receptorbiogenic aminecalcium channelDmca1Dinsectneuromodulation

Identifiers

PMID30808766
PMCPMC6397572
OpenAlexW2914312676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.