ArticleProceedings of the National Academy of Sciences of the United States of America2019
Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome
Abstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Spectroscopic elucidation of an electron-delocalized copper-tyrosine state in heme-copper oxidases reveals its role in proton pumping.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Unsymmetric bimetallic centres in metalloproteins and synthetic models.Nature reviews. Chemistry · 2026Review
- Minimized sample consumption for time-resolved serial crystallography applied to the redox cycle of human NQO1.Communications chemistry · 2026Article
- Sample delivery methods for protein X-ray crystallography with a special focus on sample consumption.Nature communications · 2025Review
- Identification of CO-binding modes in the CuThe FEBS journal · 2025Article
- Advances in microfluidic mixers for time-resolved structural biology with X-rays.Biophysical reviews · 2025Review
- XFEL crystallography reveals catalytic cycle dynamics during non-native substrate oxidation by cytochrome P450BM3.Communications chemistry · 2025Article
- Exploiting fourth-generation synchrotron radiation for enzyme and photoreceptor characterization.IUCrJ · 2025Article
- Structural and functional mechanisms of cytochrome c oxidase.Journal of inorganic biochemistry · 2025Review
- Innovative Strategies in X-ray Crystallography for Exploring Structural Dynamics and Reaction Mechanisms in Metabolic Disorders.Journal of personalized medicine · 2024Review
- Article
- Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochromeScience advances · 2023Article
- Heme-copper and Heme OJournal of inorganic biochemistry · 2023Review
- Review of serial femtosecond crystallography including the COVID-19 pandemic impact and future outlook.Structure (London, England : 1993) · 2023Review
- Going around the Kok cycle of the water oxidation reaction with femtosecond X-ray crystallography.IUCrJ · 2023Article
- Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs.IUCrJ · 2023Article
- Detection of a Geminate Photoproduct of Bovine CytochromeJournal of the American Chemical Society · 2023Article
- Structural insights into functional properties of the oxidized form of cytochrome c oxidase.Nature communications · 2023Article
- Heterogeneity in M. tuberculosis β-lactamase inhibition by Sulbactam.Nature communications · 2023Article
- Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser.Structure (London, England : 1993) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Izumi IshigamiDepartment of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461.ORCID 0000-0001-6929-1908
Ariel Lewis-BallesterDepartment of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461.
Austin EchelmeierBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Gerrit BrehmBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Nadia A ZatsepinBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Thomas D GrantHauptman-Woodward Institute and SUNY University of Buffalo, Buffalo, NY 14203.
Jesse D CoeBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Stella LisovaBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Garrett NelsonBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Shangji ZhangBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Zachary F DobsonBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Sébastien BoutetSLAC National Accelerator Laboratory, Menlo Park, CA 94025.
Raymond G SierraSLAC National Accelerator Laboratory, Menlo Park, CA 94025.
Alexander BatyukSLAC National Accelerator Laboratory, Menlo Park, CA 94025.ORCID 0000-0002-9393-2880
Petra FrommeBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Raimund FrommeBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
John C H SpenceBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Alexandra RosBiodesign Center for Applied Structural Discovery, The Biodesign Institute, Arizona State University, Tempe, AZ 85287.
Syun-Ru YehDepartment of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461.ORCID 0000-0002-9858-386X
Denis L RousseauDepartment of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461; denis.rousseau@einstein.yu.edu.
Funding
Femtosecond nano-crystallography of membrane proteinsR01GM095583 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI FROMME, PETRA · 2010 to 2023
$4.3MStructure and Function of Heme-based DioxygenasesR01GM115773 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI YEH, SYUN-RU · 2016 to 2023
$3.3MStructures of time-resolved intermediates in cytochrome c oxidase obtained by serial femtosecond crystallographyR01GM126297 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DENIS L. ROUSSEAU · 2017 to 2026
$3.2MMechanisms of Energy Transduction in Heme-Copper OxidasesR01GM098799 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ROUSSEAU, DENIS L. · 2011 to 2014
$1.8M3D NanoprinterS10OD021816 · OD · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SPENCE, JOHN CHARLES · 2016 to 2016
$659kNIGMS NIH HHS R01 GM095583NIGMS NIH HHS R01 GM098799NIGMS NIH HHS R01 GM115773NIGMS NIH HHS R01 GM126297NIH HHS S10 OD021816
Abstract
Cytochrome
Indexed as
AnimalsCatalysisCatalytic DomainCattleCopperCrystallography, X-RayElectron Transport Complex IVHemeIronOxidation-ReductionOxygenProtein ConformationCopperElectron Transport Complex IVHemeIronOxygenbioenergeticscatalytic intermediatescomplex IVcrystallographyX-ray free electron laser
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.