Evidence map›Paper›PMID 30808708›Full record

ArticleThe Journal of biological chemistry2019

A mutually induced conformational fit underlies Ca

Crystal R Archer, Benjamin T Enslow, Alexander B Taylor, Victor De la Rosa, Akash Bhattacharya, Mark S Shapiro

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Calmodulin assists during co-translational folding of the KProtein science : a publication of the Protein Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Kv7 Channels and Excitability Disorders.Handbook of experimental pharmacology · 2021
    Article
  9. Atomistic Insights of Calmodulin Gating of Complete Ion Channels.International journal of molecular sciences · 2020
    Review
  10. Pharmacological Manipulation of KFrontiers in physiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Crystal R ArcherFrom the Departments of Cell and Integrative Physiology, University of Texas Health San Antonio, San Antonio, Texas 78229; Departments of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas 78229.
Benjamin T Enslowthe Long School of Medicine, University of Texas Health San Antonio, San Antonio, Texas 78229.
Alexander B TaylorDepartments of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas 78229.
Victor De la RosaFrom the Departments of Cell and Integrative Physiology, University of Texas Health San Antonio, San Antonio, Texas 78229.
Akash BhattacharyaDepartments of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas 78229.
Mark S ShapiroFrom the Departments of Cell and Integrative Physiology, University of Texas Health San Antonio, San Antonio, Texas 78229. Electronic address: shapirom@uthscsa.edu.
The University of Texas Health Science Center at San Antonio · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1M
User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI STEVEN E EALICK · 2018 to 2026
$34.2M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
PATHOBIOLOGY OF OCCLUSIVE VASCULAR DISEASET32HL007446 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Jean Chrisostome Bopassa · 1985 to 2026
$8.9M
San Antonio Biomedical Education and ResearchK12GM111726 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LECHLEITER, JAMES D, OYAJOBI, BABATUNDE OLUKAYODE · 2015 to 2024
$7.6M
Modulation of Neuronal Ion Channels by 2nd MessengersR01NS043394 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2002 to 2014
$4.5M
Targeting specific interactions between A-kinase Anchoring Proteins (AKAPs) and ion channels with cell-permeant peptides as a novel mode of therapeutic intervention against pain disordersR01NS094461 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2015 to 2019
$2.0M
Pixel Array Detector for Macromolecular CrystallographyS10OD021527 · OD · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2016 to 2016
$2.0M
Retroviral capsid recognition by TRIM5alpha restriction factorsR01AI104476 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI IVANOV, DMITRI N · 2014 to 2018
$1.8M
Mechanism and functional role of AKAP79/150 in M current control and excitabilityR01NS065138 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2009 to 2010
$788k
Mechanism and functional role of AKAP79/150 in M current controlR56NS065138 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2012 to 2012
$465k
Biophysical interactions of PIP2 and calmodulin with KCNQ (Kv7) K+ ion channelsF31NS090887 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ARCHER, CRYSTAL RAE · 2014 to 2017
$72k
NCATS NIH HHS UL1 TR001120NCI NIH HHS P30 CA054174NHLBI NIH HHS T32 HL007446NIAID NIH HHS R01 AI104476NIGMS NIH HHS K12 GM111726NIGMS NIH HHS P30 GM124165NIH HHS S10 OD021527NINDS NIH HHS F31 NS090887NINDS NIH HHS R01 NS043394NINDS NIH HHS R01 NS065138NINDS NIH HHS R01 NS094461NINDS NIH HHS R56 NS065138
6 · The paper itself

Abstract

Calmodulin (CaM) conveys intracellular Ca

Indexed as

AnimalsCalciumCalmodulinCHO CellsCricetulusCrystallography, X-RayHumansIon Channel GatingKCNQ Potassium ChannelsProtein DomainsProtein Structure, SecondaryCalciumCalmodulinKCNQ4 protein, humanKCNQ Potassium Channelsbiophysical chemical analysiscalcium-binding proteincalcium signalingcalmodulin (CaM)conformational changeisothermal titration calorimetry (ITC)M currentmicroscale thermophoresis (MST)nuclear magnetic resonance (NMR)potassium channelpotassium voltage-gated channel subfamily Q member (KCNQ)X-ray crystallography

Identifiers

PMID30808708
PMCPMC6463706
OpenAlexW2917079697

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.