Evidence map›Paper›PMID 30808656›Full record

ArticleGenes & development2019

DNA polymerase θ accomplishes translesion synthesis opposite 1,N

Jung-Hoon Yoon, Robert E Johnson, Louise Prakash, Satya Prakash

Erratum issuedAbstract read
In one paragraph

Article in Genes & development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Catalytic Activity of Human REV1 on Undamaged and Damaged DNA.International journal of molecular sciences · 2024
    Article
  7. Article
  8. DNA Alkylation Damage by Nitrosamines and Relevant DNA Repair Pathways.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Genome Protection by DNA Polymerase θ.Annual review of genetics · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jung-Hoon YoonDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, Texas 77555, USA.
Robert E JohnsonDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, Texas 77555, USA.
Louise PrakashDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, Texas 77555, USA.
Satya PrakashDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, Texas 77555, USA.

Funding

Role of cohesin in lesion bypass in DNA damaged human cellsR01ES022948 · NIEHS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PRAKASH, LOUISE · 2014 to 2018
$1.7M
Structure and function of DNA polymerase lambda opposite DNA lesions which disrupt Watson-Crick base pairingR01GM126087 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PRAKASH, LOUISE · 2018 to 2021
$1.0M
NIEHS NIH HHS R01 ES022948NIGMS NIH HHS R01 GM126087
6 · The paper itself

Abstract

Here we show that translesion synthesis (TLS) opposite 1,N

Indexed as

Catalytic DomainDeoxyadenosinesDNA AdductsDNA-Directed DNA PolymeraseDNA Polymerase thetaDNA ReplicationHumans1,N(6)-ethenodeoxyadenosineDeoxyadenosinesDNA AdductsDNA-Directed DNA PolymeraseDNA Polymerase thetaDNA polymerase θHoogsteen base pairingtranslesion synthesisεdA lesion

Identifiers

PMID30808656
PMCPMC6411006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.