ArticleClinical chemistry2019
Polygenic Risk Scores That Predict Common Diseases Using Millions of Single Nucleotide Polymorphisms: Is More, Better?
Article in Clinical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Article
- Exploring the genetics of airflow limitation in lung function across the lifespan - a polygenic risk score study.EClinicalMedicine · 2024Article
- A Polygenic Risk Analysis for Identifying Ulcerative Colitis Patients with European Ancestry.Genes · 2024Article
- Lifestyle predictors of colorectal cancer in European populations: a systematic review.BMJ nutrition, prevention & health · 2024Article
- Evaluating the Classification Accuracy of Expression Quantitative Trait Loci Calculated Polygenic Risk Scores in Alzheimer's Disease.International journal of molecular sciences · 2023Article
- Modifiable cardiovascular risk factors and genetics for targeted prevention of dementia.European heart journal · 2023Article
- The clinical utility of the BMD-related comprehensive genome-wide polygenic score in identifying individuals with a high risk of osteoporotic fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Article
- The necessity of incorporating non-genetic risk factors into polygenic risk score models.Scientific reports · 2023Article
- Polygenic risk scores in pharmacogenomics: opportunities and challenges-a mini review.Frontiers in genetics · 2023Review
- Article
- Could Artificial Intelligence/Machine Learning and Inclusion of Diet-Gut Microbiome Interactions Improve Disease Risk Prediction? Case Study: Coronary Artery Disease.Frontiers in microbiology · 2022Review
- A catalog of curated breast cancer genes.Breast cancer research and treatment · 2022Article
- Polygenic Risk Score in African populations: progress and challenges.F1000Research · 2022Review
- The importance of increasing population diversity in genetic studies of type 2 diabetes and related glycaemic traits.Diabetologia · 2021Review
- Statistical genetics and polygenic risk score for precision medicine.Inflammation and regeneration · 2021Review
- Parkinson's disease determinants, prediction and gene-environment interactions in the UK Biobank.Journal of neurology, neurosurgery, and psychiatry · 2020Article
- Tutorial: a guide to performing polygenic risk score analyses.Nature protocols · 2020Review
- Genetic testing for neurodegenerative diseases: Ethical and health communication challenges.Neurobiology of disease · 2020Review
- Clinical applications of polygenic breast cancer risk: a critical review and perspectives of an emerging field.Breast cancer research : BCR · 2020Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
30808642What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.