ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2019
Prevalence of lung function impairment in cured pulmonary tuberculosis patients in Cotonou, Benin.
Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 7 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 7 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: a systematic review.BMC infectious diseases · 2026Pooled it
- Prevalence and associated factors of post-tuberculosis lung disease in Sub-Saharan Africa: a systematic review and meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Post-pulmonary tuberculosis lung function: a systematic review and meta-analysis.The Lancet. Global health · 2025Pooled it
- Effect of Human Immunodeficiency Virus on Lung Function and Structure: A Systematic Review and Meta-Analysis.Annals of the American Thoracic Society · 2025Pooled it
- Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14 621 people.European respiratory review : an official journal of the European Respiratory Society · 2023Pooled it
- Lung cancer occurrence after an episode of tuberculosis: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Tuberculosis related disability: a systematic review and meta-analysis.BMC medicine · 2021Pooled it
- Delays in Tuberculosis Treatment Among People With Pulmonary Tuberculosis in East Africa: Findings From a Prospective Cohort Study.Open forum infectious diseases · 2026Article
- Lung function impairment at pulmonary TB and HIV/TB diagnosis: a South African cross-sectional cohort analysis.BMJ open respiratory research · 2026Article
- Implications of reference equations for interpretation of spirometry in three African countries: a cross-sectional study.ERJ open research · 2025Article
- "I live with pain, it cannot go away": Lived experiences of childhood and adolescent pulmonary tuberculosis survivors - a qualitative study.PLOS global public health · 2025Article
- Lung function of tuberculosis patients after completion of treatment in Sidama, South Ethiopia.Frontiers in medicine · 2025Article
- Lung function and health-related quality of life among adult patients following pulmonary TB treatment.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024Article
- Managing Comorbidities, Determinants and Disability at Start and End of TB Treatment under Routine Program Conditions in China.Tropical medicine and infectious disease · 2023Article
- The Long-Term Impact of Early-Life Tuberculosis Disease on Child Health: A Prospective Birth Cohort Study.American journal of respiratory and critical care medicine · 2023Article
- Article
- COPD in People with HIV: Epidemiology, Pathogenesis, Management, and Prevention Strategies.International journal of chronic obstructive pulmonary disease · 2023Review
- Differences in CT imaging signs between patients with tuberculosis and those with tuberculosis and concurrent lung cancer.American journal of translational research · 2022Article
- Magnitude and factors associated with post-tuberculosis lung disease in low- and middle-income countries: A systematic review and meta-analysis.PLOS global public health · 2022Article
- Is It Feasible to Conduct Post-Tuberculosis Assessments at the End of Tuberculosis Treatment under Routine Programmatic Conditions in China?Tropical medicine and infectious disease · 2021Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
settingNational teaching hospital for the management of respiratory diseases, Cotonou, Benin.
objective1) To estimate the prevalence of lung function impairment (LFI) and associated factors in patients cured of pulmonary tuberculosis (PTB); and 2) to determine the link between human immunodeficiency virus (HIV) infection and LFI occurrence.
designWe performed a cross-sectional study in cured patients with smear-positive TB (PTB+) treated between 2012 and 2015. We recruited two control groups of 70 HIV-infected (HIV+/TB-) and 70 HIV-negative participants without TB (HIV-/TB-). We performed spirometry in all participants to identify LFI (obstructive, restrictive or mixed) and the 6-min walk test (6-MWT) in PTB+ participants. We assessed the factors associated with LFI using logistic regression.
resultsOf 4711 subjects with PTB, 241 were contacted and 189 were included. The median age was 37 years; 128 (68.0%) were male. Overall, 85 cured PTB+ patients had LFI (45.0%). Extent of initial radiological lesions, time between symptom onset and treatment, and female sex were independently associated with LFI. Fifty-five (29.1%) cured PTB+ patients had an abnormal 6-MWT; those with LFI had a higher risk of poor exercise tolerance (OR 2.23; interquartile range 1.16-4.30). We did not find any association between HIV infection and LFI.
conclusionLFI is very common in cured PTB+ patients from Benin and significantly impacts exercise tolerance.
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