Evidence map›Paper›PMID 30808378›Full record

ReviewBiology direct2019

Genome and pan-genome analysis to classify emerging bacteria.

Aurélia Caputo, Pierre-Edouard Fournier, Didier Raoult

Open access · goldAbstract readReview
In one paragraph

Review in Biology direct, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Microbial Evolution and Systematics: Archaea and Bacteria.Progress in molecular and subcellular biology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Genomic diversity and functional adaptation ofFrontiers in microbiology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Genomic Insights into Cyanide Biodegradation in theInternational journal of molecular sciences · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Aurélia CaputoAix Marseille Univ, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France.
Pierre-Edouard FournierAix Marseille Univ, IRD, APHM, SSA, VITROME, IHU-Méditerranée Infection, Marseille, France.
Didier RaoultAix Marseille Univ, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France. didier.raoult@gmail.com.
Méditerranée Infection Foundation · FRInstitut de Recherche pour le Développement · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the recent years, genomic and pan-genomic studies have become increasingly important. Culturomics allows to study human microbiota through the use of different culture conditions, coupled with a method of rapid identification by MALDI-TOF, or 16S rRNA. Bacterial taxonomy is undergoing many changes as a consequence. With the help of pan-genomic analyses, species can be redefined, and new species definitions generated.

resultsGenomics, coupled with culturomics, has led to the discovery of many novel bacterial species or genera, including Akkermansia muciniphila and Microvirga massiliensis. Using the genome to define species has been applied within the genus Klebsiella. A discontinuity or an abrupt break in the core/pan-genome ratio can uncover novel species.

conclusionsApplying genomic and pan-genomic analyses to the reclassification of other bacterial species or genera will be important in the future of medical microbiology. The pan-genome is one of many new innovative tools in bacterial taxonomy. REVIEWERS: This article was reviewed by William Martin, Eric Bapteste and James Mcinerney. OPEN PEER REVIEW: Reviewed by William Martin, Eric Bapteste and James Mcinerney.

Indexed as

MicrobiotaBacteriaGenomicsHumansRNA, BacterialRNA, Ribosomal, 16SSequence Analysis, RNASpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationRNA, BacterialRNA, Ribosomal, 16SGenomicNovel speciesPan-genomeTaxonomy

Identifiers

PMID30808378
PMCPMC6390601
OpenAlexW2940320699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.