ArticleBMC complementary and alternative medicine2019
Compounds from Olea europaea and Pistacia lentiscus inhibit oral microbial growth.
Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Role of Astaxanthin as an Antioxidant and Anti-Inflammatory Agent in Human Health: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- Systematic review and meta-analysis on the effect of olive oil in the treatment of periodontal diseases.Frontiers in oral health · 2025Pooled it
- Randomized clinical trial on the clinical effects of a toothpaste containing extra virgin olive oil, xylitol, and betaine in gingivitis.Scientific reports · 2023Trial
- Olive oil-based interventions for gingival inflammation and plaque control- A systematic review of clinical evidence.Journal of Ayurveda and integrative medicine · 2026Review
- Formulation and Characterization of an Oleuropein-Enriched Oral Spray Gel: Microbiological Performance and In Ovo Histopathological Safety.Pharmaceutics · 2026Article
- Antimicrobial, Anti-Biofilm Activity and Antioxidants of Phenolic Compounds Isolated FromFood science & nutrition · 2025Article
- In Silico Docking of Medicinal Herbs Against P. gingivalis for Chronic Periodontitis Intervention.International dental journal · 2025Article
- Anacardiaceae Family: Effect of Isolated Compounds and Other Identified Phytochemicals Against Clinically RelevantAntibiotics (Basel, Switzerland) · 2025Review
- Article
- Article
- Biological Activities of Novel Oleanolic Acid Derivatives from Bioconversion and Semi-Synthesis.Molecules (Basel, Switzerland) · 2024Review
- Review
- Effects of Oleanolic Acid Derived from Wine Pomace on Periodontopathic Bacterial Growth in Healthy Individuals: A Randomized Placebo-Controlled Study.Dentistry journal · 2024Article
- Extra Virgin Olive Oil-Based Formulations: A "Green" Strategy againstInternational journal of molecular sciences · 2023Article
- Mastic (Pistacia lentiscus) gum and oral health: a state-of-the-art review of the literature.Journal of natural medicines · 2023Review
- Antimicrobial Efficiency ofMicroorganisms · 2023Review
- A Review ofPlants (Basel, Switzerland) · 2023Review
- Biosynthesis of phyto-functionalized silver nanoparticles using olive fruit extract and evaluation of their antibacterial and antioxidant properties.Frontiers in chemistry · 2023Article
- Evaluation of Chitosan-Oleuropein Nanoparticles on the Durability of Dentin Bonding.Drug design, development and therapy · 2023Article
- Strategies to Combat Caries by Maintaining the Integrity of Biofilm and Homeostasis during the Rapid Phase of Supragingival Plaque Formation.Antibiotics (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundIn view of the increasing antibiotic resistance, the introduction of natural anti-infective agents has brought a new era in the treatment of bacterially derived oral diseases.
methodsThe aim of this study was to investigate the antimicrobial potential of five natural constituents of Olea europaea (oleuropein, maslinic acid, hydroxytyrosol, oleocanthal, oleacein) and three compounds of Pistacia lentiscus (24Z-isomasticadienolic acid, oleanolic acid, oleanonic aldehyde) against ten representative oral bacterial species and a Candida albicans strain. After the isolation and quality control of natural compounds, the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) assay were performed.
resultsAmong all O. europaea-derived constituents, maslinic acid was the most active (MIC = 4.9-312 μg mL
conclusionsOverall, maslinic acid and oleanolic acid exerted the most significant inhibitory activity against the tested oral pathogens, especially streptococci and anaerobic oral microorganisms.
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Registered trials
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