ArticleBMC genomics2019
Gene regulation of Sclerotinia sclerotiorum during infection of Glycine max: on the road to pathogenesis.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 53 citations in OpenAlex.
- Comparative transcriptome analysis reveals underlying aggressiveness mechanisms of Sclerotinia sclerotiorum infecting Brassica juncea.Archives of microbiology · 2026Article
- Revealing the early pathogenic mechanisms of Agroatehlia rolfsii in Arachis hypogaea through RNA-seq and identification of ArNIS1-like effectors.BMC plant biology · 2026Article
- Article
- A fungal effector promotes infection via stabilizing a negative regulatory factor of chloroplast immunity.Nature communications · 2025Article
- Neutral transcriptome rewiring promotes quantitative disease resistance evolvability at the species level.The Plant cell · 2025Article
- Assessment of potential candidate genes for partial resistance to Sclerotinia stem rot caused by Sclerotinia sclerotiorum using real-time quantitative PCR.The plant genome · 2025Article
- SsNEP2 Plays a Role in the Interaction BetweenJournal of fungi (Basel, Switzerland) · 2025Article
- Modelling metabolic fluxes of tomato stems reveals that nitrogen shapes central metabolism for defence against Botrytis cinerea.Journal of experimental botany · 2024Article
- A single laccase acts as a key component of environmental sensing in a broad host range fungal pathogen.Communications biology · 2024Article
- The broad host range pathogen Sclerotinia sclerotiorum produces multiple effector proteins that induce host cell death intracellularly.Molecular plant pathology · 2023Article
- Review
- Fungal biotechnology: From yesterday to tomorrow.Frontiers in fungal biology · 2023Review
- A broadly conserved fungal alcohol oxidase (AOX) facilitates fungal invasion of plants.Molecular plant pathology · 2023Article
- Article
- Population and genome-wide association studies ofFrontiers in microbiology · 2023Article
- Alternative splicing reprogramming in fungal pathogenFrontiers in plant science · 2022Article
- Identification of reference genes and their validation for gene expression analysis in phytopathogenic fungus Macrophomina phaseolina.PloS one · 2022Article
- ε-poly-Journal of fungi (Basel, Switzerland) · 2021Article
- Article
- Analysis of differentially expressed Sclerotinia sclerotiorum genes during the interaction with moderately resistant and highly susceptible chickpea lines.BMC genomics · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSclerotinia sclerotiorum is a broad-host range necrotrophic pathogen which is the causative agent of Sclerotinia stem rot (SSR), and a major disease of soybean (Glycine max). A time course transcriptomic analysis was performed in both compatible and incompatible soybean lines to identify pathogenicity and developmental factors utilized by S. sclerotiorum to achieve pathogenic success.
resultsA comparison of genes expressed during early infection identified the potential importance of toxin efflux and nitrogen metabolism during the early stages of disease establishment. The later stages of infection were characterized by an apparent shift to survival structure formation. Analysis of genes highly upregulated in-planta revealed a temporal regulation of hydrolytic and detoxification enzymes, putative secreted effectors, and secondary metabolite synthesis genes. Redox regulation also appears to play a key role during the course of infection, as suggested by the high expression of genes involved in reactive oxygen species production and scavenging. Finally, distinct differences in early gene expression were noted based on the comparison of S. sclerotiorum infection of resistant and susceptible soybean lines.
conclusionsAlthough many potential virulence factors have been noted in the S. sclerotiorum pathosystem, this study serves to highlight soybean specific processes most likely to be critical in successful infection. Functional studies of genes identified in this work are needed to confirm their importance to disease development, and may constitute valuable targets of RNAi approaches to improve resistance to SSR.
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