ArticleBMC microbiology2019
A coumarin analogue NFA from endophytic Aspergillus fumigatus improves drought resistance in rice as an antioxidant.
Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 57 citations in OpenAlex.
- Dual legacy of plant water-deficit-tolerance and watering history shapes rhizosphere microbial transplant outcomes in tomato post-drought recovery.Environmental microbiome · 2026Article
- Host genotype and environment shape rhizosphere and root microbiome composition of pecan rootstocks.Frontiers in microbiomes · 2026Article
- Metagenomic and Metabolomic Perspectives on the Drought Tolerance of Broomcorn Millet (Microorganisms · 2025Article
- Review
- Multifarious Characterization and Efficacy of Three Phosphate-SolubilizingPlants (Basel, Switzerland) · 2023Article
- Promising drought and salinity tolerance features of3 Biotech · 2023Article
- Identification of a Novel Coumarins Biosynthetic Pathway in the Endophytic Fungus Fusarium oxysporum GU-7 with Antioxidant Activity.Applied and environmental microbiology · 2023Article
- Living Fungi in an Opencast Limestone Mine: Who Are They and What Can They Do?Journal of fungi (Basel, Switzerland) · 2022Article
- The influence of endophytes on rice fitness under environmental stresses.Plant molecular biology · 2022Review
- Inhibition ofJournal of fungi (Basel, Switzerland) · 2022Article
- Article
- Plants and endophytes - a partnership for the coumarin production through the microbial systems.Mycology · 2022Review
- Study on Secondary Metabolites of Endophytic Fungus,International journal of analytical chemistry · 2022Article
- Intimate genetic relationships and fungicide resistance in multiple strains of Aspergillus fumigatus isolated from a plant bulb.Environmental microbiology · 2021Article
- Microbial Diversity of Upland Rice Roots and Their Influence on Rice Growth and Drought Tolerance.Microorganisms · 2020Article
- Fungal and Bacterial Microbiome Associated with the Rhizosphere of Native Plants from the Atacama Desert.Microorganisms · 2020Article
- Bacterial Blight Induced Shifts in Endophytic Microbiome of Rice Leaves and the Enrichment of Specific Bacterial Strains With Pathogen Antagonism.Frontiers in plant science · 2020Article
- Elucidating Mechanisms of Endophytes Used in Plant Protection and Other Bioactivities With Multifunctional Prospects.Frontiers in bioengineering and biotechnology · 2020Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDrought and its resulting oxidative damage are the major yield limiting factors for crops in arid and semi-arid regions. Recent studies have found that endophytic fungi coexisting in plants can alleviate biotic or abiotic damage to plant growth and development. In order to screen for the endophytes associated with drought stress, 12 strains of endophytic fungi with high antioxidant activity isolated from riparian plants Myricaria laxiflora were evaluated for their effects in rice by the crude extracts.
resultsOf the 12 endophytic fungi, Aspergillus fumigatus SG-17 functioned most effectively, with the crude extract exhibiting relatively higher antioxidant capacity both in vivo and in vitro. The subsequent MS and NMR analysis showed that the primary substance responsible for the antioxidant activity in the extract was (Z)-N-(4-hydroxystyryl) formamide (NFA), an analogue of coumarin. Enzyme activity assay in nerve cells SH-SY5Y showed that NFA could maintain the membrane integrity and regulate the antioxidase activity under oxidative stress. In rice suffering drought stress, NFA effectively alleviated the harm by regulating the contents of NADPH oxidases, antioxidants and heat shock proteins, all of which are closely related with the reactive oxygen species pathway.
conclusionThese findings indicated that some endophytes from plants often subjected to flooding and oxidative stress could enhance drought resistance by producing compounds such as NFA to regulate the oxidative pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.