Evidence map›Paper›PMID 30807854›Full record

ArticleBiochimica et biophysica acta. Gene regulatory mechanisms2019

Cytosine methylation of mitochondrial DNA at CpG sequences impacts transcription factor A DNA binding and transcription.

Vishantie Dostal, Mair E A Churchill

Open access · greenAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Gene regulatory mechanisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Cytosine methylase and hydroxymethylase activity in mammalian mitochondria.Frontiers in cell and developmental biology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Changes in Mitochondrial Epigenome in Type 2 Diabetes Mellitus.British journal of biomedical science · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Mitochondrial DNA Methylation and Human Diseases.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vishantie DostalProgram in Structural Biology and Biochemistry, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Mair E A ChurchillDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Program in Structural Biology and Biochemistry, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: Mair.Churchill@ucdenver.edu.
University of Colorado Denver · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
Structural and Functional Studies of the Histone Chaperone CAF-1R01GM111902 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI CHURCHILL, MAIR E · 2014 to 2017
$1.2M
NCI NIH HHS P30 CA046934NIGMS NIH HHS R01 GM111902
6 · The paper itself

Abstract

In eukaryotes, cytosine methylation of nuclear DNA at CpG sequences (

Indexed as

CpG IslandsDNA MethylationTranscription, GeneticCytosineDNA-Binding ProteinsDNA, MitochondrialHumansMitochondriaMitochondrial ProteinsPromoter Regions, GeneticProtein BindingProtein MultimerizationTranscription FactorsCytosineDNA-Binding ProteinsDNA, MitochondrialMitochondrial ProteinsTFAM protein, humanTranscription FactorsCpG methylationDNA bindingMitochondrial DNATFAMTranscription

Identifiers

PMID30807854
PMCPMC7806247
OpenAlexW2915087387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.