ArticleMedical care2019
Ascertainment of Aspirin Exposure Using Structured and Unstructured Large-scale Electronic Health Record Data.
Article in Medical care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Semaglutide and Cardiovascular Outcomes According to Baseline Aspirin Use: Analyses of the SOUL and SELECT Trials.Diabetes, obesity & metabolism · 2026Article
- Ascertaining accurate exposure to aspirin and other antithrombotic medications using structured electronic health record data.Research and practice in thrombosis and haemostasis · 2024Article
- Home medication inventory method to assess over-the-counter (OTC) medication possession and use: A pilot study on the feasibility of in-person and remote modalities with older adults.Research in social & administrative pharmacy : RSAP · 2024Article
- Natural History of Keloids: A Sociodemographic Analysis Using Structured and Unstructured Data.Dermatology and therapy · 2024Article
- Antiplatelet treatment patterns and outcomes of secondary stroke prevention in the United States.Heliyon · 2023Article
- A strategy for validation of variables derived from large-scale electronic health record data.Journal of biomedical informatics · 2021Article
- Evaluation of Warfarin Use in Patients With Mental Health Conditions in a Rural Community Health Center System.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021Article
- Young-onset colorectal cancer risk among individuals with iron-deficiency anaemia and haematochezia.Gut · 2020Article
- Risk Factors for Early-Onset Colorectal Cancer.Gastroenterology · 2020Article
- Metformin Is Associated With Reduced Odds for Colorectal Cancer Among Persons With Diabetes.Clinical and translational gastroenterology · 2019Article
- Risk factors for colorectal cancer significantly vary by anatomic site.BMJ open gastroenterology · 2019Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundAspirin impacts risk for important outcomes such as cancer, cardiovascular disease, and gastrointestinal bleeding. However, ascertaining exposure to medications available both by prescription and over-the-counter such as aspirin for research and quality improvement purposes is a challenge.
objectivesDevelop and validate a strategy for ascertaining aspirin exposure, utilizing a combination of structured and unstructured data. RESEARCH
designThis is a retrospective cohort study. SUBJECTS: In total, 1,869,439 Veterans who underwent usual care colonoscopy 1999-2014 within the Department of Veterans Affairs. MEASURES: Aspirin exposure and dose were obtained from an ascertainment strategy combining query of structured medication records available in electronic health record databases and unstructured data extracted from free-text progress notes. Prevalence of any aspirin exposure and dose-specific exposure were estimated. Positive predictive value and negative predictive value were used to assess strategy performance, using manual chart review as the reference standard.
resultsOur combined strategy for ascertaining aspirin exposure using structured and unstructured data reached a positive predictive value and negative predictive value of 99.2% and 97.5% for any exposure, and 92.6% and 98.3% for dose-specific exposure. Estimated prevalence of any aspirin exposure was 36.3% (95% confidence interval: 36.2%-36.4%) and dose-specific exposure was 35.4% (95% confidence interval: 35.3%-35.5%).
conclusionsA readily accessible approach utilizing a combination of structured medication records and query of unstructured data can be used to ascertain aspirin exposure when manual chart review is impractical.
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