Evidence map›Paper›PMID 30806983›Full record

ArticleNeurotoxicity research2019

25C-NBOMe, a Novel Designer Psychedelic, Induces Neurotoxicity 50 Times More Potent Than Methamphetamine In Vitro.

Peng Xu, Qiyang Qiu, Haijie Li, Sicheng Yan, Mengxiang Yang, C Benjamin Naman, Youmei Wang, Wenhua Zhou, Haowei Shen, Wei Cui

Abstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Molecular and Medical Aspects of Psychedelics.International journal of molecular sciences · 2023
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Zebrafish andToxicology reports · 2021
    Article
  8. DARK Classics in Chemical Neuroscience: NBOMes.ACS chemical neuroscience · 2020
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Peng XuDrug Intelligence and Forensic Center, Ministry of Public Security, Beijing, China.
Qiyang QiuNingbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China.
Haijie LiNingbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China.
Sicheng YanNingbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China.
Mengxiang YangNingbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China.
C Benjamin NamanLi Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo, China.
Youmei WangDrug Intelligence and Forensic Center, Ministry of Public Security, Beijing, China.
Wenhua ZhouNingbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China.
Haowei ShenNingbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China. shenhaowei@nbu.edu.cn.
Wei CuiNingbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China. cuiwei@nbu.edu.cn.ORCID http://orcid.org/0000-0002-8645-4278
Ningbo University · CNMinistry of Public Security of the People's Republic of China · CN

Funding

LiDakSum Marine Biopharmaceutical Development Fund, and the K. C. Wong Magna Fund in Ningbo University NANingbo municipal innovation team of life science and health 2015C110026Ningbo Sci & Tech Project for Common Wealth 2017C50042the National Key Research and Development Program of China 2017YFC0803605the National Natural Science Foundation of China 81673407, 81870853, 81850410553Zhejiang Provincial Key Laboratory of Pathophysiology 201804
6 · The paper itself

Abstract

25C-NBOMe is a designer substituted phenethylamine and a high-potency psychedelic that acts on the 5-HT

Indexed as

AnimalsBenzylaminesCell Line, TumorCell SurvivalDesigner DrugsHallucinogensHumansInhibitory Concentration 50MAP Kinase Signaling SystemMethamphetamineMiceNeuronsPC12 CellsPhenethylaminesProto-Oncogene Proteins c-aktRats2-(4-chloro-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamineBenzylaminesDesigner DrugsHallucinogensMethamphetaminePhenethylaminesProto-Oncogene Proteins c-akt25C-NBOMeDesigner drugsERKGSK3βPsychedelicSubstituted phenethylamine

Identifiers

PMID30806983
OpenAlexW2916631284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.