Evidence map›Paper›PMID 30806913›Full record

ArticleObesity surgery2019

Lack of Improvement of Sperm Characteristics in Obese Males After Obesity Surgery Despite the Beneficial Changes Observed in Reproductive Hormones.

Berniza Calderón, Lydia Huerta, Julio Galindo, José Manuel González Casbas, Héctor F Escobar-Morreale, Antonia Martín-Hidalgo, José I Botella-Carretero

Abstract read
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In one paragraph

Article in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  8. The role of leptin and low testosterone in obesity.International journal of impotence research · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Berniza CalderónDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Carretera de Colmenar Km. 9.1, 28034, Madrid, Spain.
Lydia HuertaDepartment of Biochemistry-Research, Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Julio GalindoDepartment of General and Digestive Surgery, Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
José Manuel González CasbasUnit of Assisted Reproduction, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Héctor F Escobar-MorrealeDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Carretera de Colmenar Km. 9.1, 28034, Madrid, Spain.
Antonia Martín-Hidalgo *Department of Biochemistry-Research, Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
José I Botella-Carretero *Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Carretera de Colmenar Km. 9.1, 28034, Madrid, Spain. joseignacio.botella@salud.madrid.org.ORCID http://orcid.org/0000-0002-6425-2747
Centro de Investigación Biomédica en Red · ESUniversidad de Alcalá · ESHospital Universitario Ramón y Cajal · ESInstituto Ramón y Cajal de Investigación Sanitaria · ESInstituto Tecnológico de Santo Domingo · DO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEven though obesity surgery normalizes circulating testosterone concentrations in males with obesity-associated secondary hypogonadism, its impact on spermatogenesis remains controversial. We aimed to evaluate sperm characteristics in obese men after bariatric surgery as well as changes in reproductive hormones.

methodsTwenty severely obese men (body mass index (BMI) ≥ 35 kg/m

resultsAfter surgery, serum total testosterone, calculated free testosterone, inhibin B, and kisspeptin increased, whereas fasting insulin, HOMA-IR, and leptin concentrations decreased. Despite these improvements, sperm volume showed a small decrease after surgery, while the rest of sperm characteristics remained mostly unchanged. Abnormal sperm concentration persisted in 60% of the patients.

conclusionsSperm characteristics may not improve after bariatric surgery despite the beneficial changes of reproductive hormones.

Indexed as

Bariatric SurgeryAdultBody Mass IndexFollow-Up StudiesGonadal Steroid HormonesHumansHypogonadismInfertility, MaleInhibinsInsulinLeptinMaleMiddle AgedObesity, MorbidPostoperative PeriodPrognosisGonadal Steroid Hormonesinhibin BInhibinsInsulinLeptinTestosteroneBariatric surgeryKisspeptinLeptinMale infertilityObesitySemen analysis

Identifiers

PMID30806913
OpenAlexW2916751356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.