Evidence map›Paper›PMID 30806897›Full record

ArticleCell stress & chaperones2019

Effects of cobalt chloride on the stem cell marker expression and osteogenic differentiation of stem cells from human exfoliated deciduous teeth.

Yijing Chen, Qi Zhao, Xin Yang, Xinlin Yu, Dongsheng Yu, Wei Zhao

Abstract read
In one paragraph

Article in Cell stress & chaperones, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Erythroid Cells as Full Participants in the Tumor Microenvironment.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Review
  7. [Hypoxia promotes differentiation of human induced pluripotent stem cells into embryoid bodiesNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yijing ChenGuanghua School of Stomatology, Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, No. 56 Lingyuan West Road, Guangzhou, 510055, China.
Qi ZhaoXianning Central Hospital, The First Affiliated Hospital Of Hubei University of Science and Technology, Xianning, 437000, China.
Xin YangGuanghua School of Stomatology, Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, No. 56 Lingyuan West Road, Guangzhou, 510055, China.
Xinlin YuInternational Department, The Affiliated High School of SCNU, Guangzhou, 510630, China.
Dongsheng YuGuanghua School of Stomatology, Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, No. 56 Lingyuan West Road, Guangzhou, 510055, China. yudsh@mail.sysu.edu.cn.
Wei ZhaoGuanghua School of Stomatology, Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, No. 56 Lingyuan West Road, Guangzhou, 510055, China. zhaowei3@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-0251-8084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells from human exfoliated deciduous teeth (SHEDs) are a promising source for tissue engineering and stem cell transplantation. However, long-term in vitro culture and expansion lead to the loss of stemness of SHEDs, compromising their therapeutic benefits. Hypoxia plays an essential role in controlling the stem cell behavior of mesenchymal stem cells (MSCs). Thus, this study aimed to investigate the effects of cobalt chloride (CoCl

Indexed as

BiomarkersCell DifferentiationCell ProliferationCells, CulturedChildCobaltHealthy VolunteersHumansMesenchymal Stem CellsOsteogenesisTooth, DeciduousBiomarkersCobaltcobaltous chlorideCobalt chlorideDeciduous teethDental pulpOsteogenic differentiationStem cellsStemness

Identifiers

PMID30806897
PMCPMC6527733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.