Evidence map›Paper›PMID 30806875›Full record

SynthesisJournal of cancer survivorship : research and practice2019

High-intensity interval training in the therapy and aftercare of cancer patients: a systematic review with meta-analysis.

Hendrik Mugele, Nils Freitag, Jannik Wilhelmi, Yanxiang Yang, Sulin Cheng, Wilhelm Bloch, Moritz Schumann

3 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 42 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04679233 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

Feasibility and Preliminary Efficacy of Aerobic Exercise in Head and Neck Cancer Patients Undergoing Radiation Therapy

TypeinterventionalSponsorVanderbilt UniversityRan2021 to 2021Enrolled0ConditionsHead and Neck Neoplasm, RadiotherapyArmsPrescription aerobic exercise
NCT06190600 naactive not recruitingnot on this map

Supervised Physical Activity in Young Women With Early Breast Cancer During Neoadjuvant Chemotherpy

TypeinterventionalSponsorThe Greater Poland Cancer CentreRan2018 to 2026Enrolled40ConditionsBreast CancerArmsHigh Intensity Interval Training (HIIT), neoadjuvant treatment (doxorubicin, cyclophosphamide, paclitaxel, trastuzumab, pertuzumab), Standard Supportive Care
NCT06336070 narecruitingnot on this mapstarted 2024, after this paper: background citation

Postmenopausal Oncological Women Exercising for Recover Their Health. Associations and Changes in Metabolic Flexibility and Autonomic Control After Two Training Programs (Muscle Power vs Metabolic Power): the POWER Health Study

TypeinterventionalSponsorUniversity of ValenciaRan2024 to 2028Enrolled56ConditionsBreast Cancer Female, Cardiometabolic Syndrome, Metabolism Disorder, Lipid, Autonomic DysfunctionArmsHIIT program (8 weeks), MPI program (8 weeks)
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  7. High-intensity interval training effects in cardiorespiratory fitness of lung cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  9. High-intensity interval training in the prehabilitation of cancer patients-a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  17. Effect of high-intensity interval training on patient-reported outcomes and physical function in women with breast cancer receiving anthracycline-based chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  20. In-hospital moderate intensity interval training following surgical resection of foregut malignancy - a prospective single arm feasibility study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hendrik MugeleDepartment of Sport Science, University of Innsbruck, Innsbruck, Austria.
Nils FreitagDepartment of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany.
Jannik WilhelmiDepartment of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany.
Yanxiang YangDepartment of Physical Education, Exercise, Health and Technology Centre, Shanghai Jiao Tong University, Shanghai, China.
Sulin ChengDepartment of Physical Education, Exercise, Health and Technology Centre, Shanghai Jiao Tong University, Shanghai, China.
Wilhelm BlochDepartment of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany.
Moritz SchumannDepartment of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany. m.schumann@dshs-koeln.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis review and meta-analysis aimed to evaluate the effects of high-intensity interval training (HIIT) compared to usual care (UC) or moderate-intensity training (MIE) on physical fitness and health-related outcomes in cancer patients across all stages of therapy and aftercare.

methodsDatabases were systematically searched in accordance with the PRISMA guidelines until October 4th, 2018. Eligibility criteria included adult patients of various cancer types, performing HIIT vs. UC or MIE. Outcomes of interest included physical fitness (cardiorespiratory fitness [VO

resultsThe search identified 1453 studies, out of which 12 articles were included. The average duration of interventions was 6.7 ± 3.0 weeks, with 2.8 ± 0.5 sessions per week. The meta-analysis for VO

conclusionThis systematic review showed that short-term HIIT induces similar positive effects on physical fitness and health-related outcomes as MIE but seems to be superior compared to UC. Thus, HIIT might be a time-efficient intervention for cancer patients across all stages of therapy and aftercare. IMPLICATIONS FOR CANCER SURVIVORS: High-intensity interval training (HIIT) is superior compared to usucal care in improving physical fitness and health-related outcomes in cancer patients across all stages of therapy and aftercare. Currently, there is no evidence for the benefits of HIIT compared to aerobic training of moderate intensity (MIE) for changes in cardiorespiratory fitness, lean mass and patient-reported outcomes. Reductions in fat mass may be more pronounced in HIIT compared to MIE when training is performed in aftercare.

Indexed as

High-Intensity Interval TrainingAdultAftercareBody CompositionCancer SurvivorsCardiorespiratory FitnessExercise TherapyFatigueHumansNeoplasmsPhysical FitnessQuality of LifeTreatment OutcomeExercise medicineExercise oncologyHIITRehabilitation

Identifiers

PMID30806875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.