ArticleInternational journal of clinical oncology2019
Long-term outcomes and prognostic factors of pulmonary metastasectomy for osteosarcoma and soft tissue sarcoma.
Article in International journal of clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A meta-analysis comparing efficiency of limb-salvage surgery vs amputation on patients with osteosarcoma treated with neoadjuvant chemotherapy.International wound journal · 2022Pooled it
- Pulmonary metastasectomy: a 14-year single-center experience and literature review.Journal of cardiothoracic surgery · 2026Review
- Stereotactic Body Radiotherapy vs. Metastasectomy for Soft Tissue and Bone Sarcoma Lung Metastases - A Systematic Review analyzing Safety and Efficacy.Clinical and translational radiation oncology · 2026Review
- Pulmonary metastasectomy from bone and soft tissue sarcomas: defining surgical indications at the time of second pulmonary recurrence.International journal of clinical oncology · 2026Article
- Article
- Resection of Recurrent Metastatic Osteosarcoma After Bilateral Pulmonary Metastasectomy.Clinical case reports · 2025Article
- Targeting metastasis in paediatric bone sarcomas.Molecular cancer · 2025Review
- Surgical Margins and Oncologic Outcomes Following Wedge Resection of Pulmonary Metastases in Pediatric and Young Adult Patients with Sarcoma.Annals of surgical oncology · 2025Article
- The Case for Pulmonary Metastasectomy-Clinical Practice Narrative Review and Commentary.Life (Basel, Switzerland) · 2024Article
- Outcomes and prognostic factors of repeat pulmonary metastasectomy.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Outcome and survival analysis of pulmonary metastasectomy for primary sarcoma with pulmonary metastases.Frontiers in surgery · 2024Article
- Improving survival after pulmonary metastasectomy for sarcoma: analysis of prognostic factors.General thoracic and cardiovascular surgery · 2023Review
- Establishment and validation of systematic prognostic nomograms in patients over 60 years of age with osteosarcoma: A multicenter external verification study.Cancer medicine · 2023Article
- Bone sarcoma follow-up; a nationwide analysis of oncological events after initial treatment.Journal of bone oncology · 2023Article
- Prognostic Factors of Pulmonary Metastasectomy for Soft Tissue Sarcomas Arising in the Trunk Wall and Extremities.Cancers · 2022Article
- Prognostic Factors for Leiomyosarcoma with Isolated Metastases to the Lungs: Impact of Metastasectomy.Annals of surgical oncology · 2022Article
- Survival and prognostic factors in patients undergoing pulmonary metastasectomy for lung metastases from retroperitoneal sarcoma.World journal of surgical oncology · 2022Article
- Surgical indication of pulmonary metastasis arising from osteosarcoma or soft tissue sarcoma.General thoracic and cardiovascular surgery · 2022Article
- Analysis of Clinical Manifestations and Prognostic Factors Affecting Osteosarcoma.Disease markers · 2022Article
- Trabectedin and Radiation Therapy for Cardiac Metastasis From Leiomyosarcoma: A Case Report and Review of the Literature.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prognostic factors of pulmonary metastasectomy in patients with osteosarcoma and soft tissue sarcoma remain controversial. The purpose of our analysis was to explore the prognostic factors and outcomes of patients with osteosarcoma and soft tissue sarcoma who underwent pulmonary metastasectomy at our institution.
methodsWe reviewed the data of 44 patients who underwent resection of pulmonary metastases from 1996 to 2016 at our institution. The Kaplan-Meier method, log-rank test and multivariate Cox hazard model were used for comparison and survival analyses.
resultsThere was no perioperative mortality. The median post-metastasectomy overall survival was 24.8 months, and the 5-year overall survival rate of all patients was 43.5%. The 5-year survival rate of the patients who underwent repeat thoracotomies was 60.0%. Incomplete resection, a largest tumor size > 2 cm and a disease-free interval < 12 months were associated with poor survival in multivariate analyses. Among eight patients, who underwent repeat pulmonary resection, two remain alive with no evidence of disease. These patients had the longest DFI and DFI-2 (time from first pulmonary metastasectomy to the diagnosis of recurrent pulmonary metastasis), respectively.
conclusionThe survival of patients with a relatively long disease-free interval, small tumor size and complete resection was favorable following the treatment of osteosarcoma and soft tissue sarcoma with pulmonary metastasectomy. Repeat pulmonary metastasectomies also provide favorable prognosis in select patients.
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