Evidence map›Paper›PMID 30806804›Full record

Observational studyEuropean radiology2019

Multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney: CT and MRI findings and clinical characteristic.

Kotaro Yoshida, Naoki Takahashi, Bernard F King, Akira Kawashima, Peter C Harris, Lynn D Cornell, Emilie Cornec-Le Gall, Dai Inoue, Ichiro Mizushima, Mitsuhiro Kawano and 3 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Kotaro YoshidaDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Naoki TakahashiDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Takahashi.Naoki@mayo.edu.
Bernard F KingDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Akira KawashimaDepartment of Radiology, Mayo Clinic, Scottsdale, AZ, USA.
Peter C HarrisDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Lynn D CornellDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Emilie Cornec-Le GallDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Dai InoueDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Ichiro MizushimaDivision of Rheumatology, Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Mitsuhiro KawanoDivision of Rheumatology, Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Eric ThervetDepartment of Nephrology, European Hospital Georges Pompidou, APHP, Paris Descartes University, Paris, France.
Paul René de CotretDepartment of Medicine, Division of Nephrology, Laval University, Quebec, Canada.
Vicente E TorresDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic · USKanazawa University · JPMayo Clinic in Arizona · USCentre Hospitalier Régional Universitaire de Brest · FRHôpital Européen Georges-Pompidou · FRUniversité Laval · CA

Funding

Pilot and FeasibilityP30DK090728 · NIDDK · MAYO CLINIC ROCHESTER · PI ROMERO, MICHAEL F. · 2010 to 2019
$11.8M
RENIN ANGIOTENSIN SYSTEM IN THE PATHOGENESIS OF ADPKDR01DK044863 · NIDDK · MAYO CLINIC ROCHESTER · PI TORRES, VICENTE E · 1991 to 2019
$4.5M
NIDDK NIH HHS P30 DK090728NIDDK NIH HHS R01 DK044863
6 · The paper itself

Abstract

purposeThe aim of this study was to clarify the radiologic and clinical characteristics of multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney.

methodFourteen patients with unique and characteristic multiple hemorrhagic subcapsular cortical cysts of the kidney, not categorized in any existing renal cystic diseases, were retrospectively reviewed. The clinical information including age, sex, symptom, family history of renal or renal cystic disease, and laboratory data were collected. CT and MRI findings including distribution, number and size of cysts, and CT attenuation and signal intensity on T1- and T2-weighted MRI of cysts were analyzed.

resultsAll patients except one were young and none had a family history of renal or renal cystic disease. Common clinical symptoms were flank or abdominal pain and hematuria. In all cases, only the left kidney was involved at initial presentation. Cysts were small (median cyst size, 4-15 mm), numerous, and distributed mainly along the subcapsular cortex of the kidney. Cysts were hyper-attenuated on unenhanced CT, extremely hypointense on T2-weighted MRI, and mildly hyperintense on T1-weighted MRI. All patients except one had normal renal function. Imaging follow-up revealed stable or mildly progressive disease in seven patients. Two patients developed several hemorrhagic subcapsular cortical cysts in the right kidney at follow-up. Three of five patients with a renal pathology specimen showed concurrent IgA nephropathy.

conclusionWe have identified a unique renal cystic disease with multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney that has a characteristic manifestation both radiologically and clinically. KEY POINTS: • Multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney is a unique non-familial renal cystic disease with a characteristic manifestation both radiologically and clinically. • Most cases of multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney are stable or slowly progressive, and do not require invasive intervention.

Indexed as

Kidney CortexAbdominal PainAdultFemaleHematuriaHemorrhageHumansKidney Diseases, CysticKidney NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedMultidetector Computed TomographyRetrospective StudiesVisceraCystsKidney cortexMagnetic resonance imagingMultidetector computed tomography

Identifiers

PMID30806804
PMCPMC6684360
OpenAlexW2915693072

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.