Evidence map›Paper›PMID 30806793›Full record

ArticleMikrochimica acta2019

ZnS quantum dots surface-loaded with zinc(II) ions as a viable fluorescent probe for glutathione.

Zahra Amouzegar, Abbas Afkhami, Tayebeh Madrakian

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zahra AmouzegarFaculty of Chemistry, Bu-Ali Sina University, Hamedan, 6517838695, Iran.
Abbas AfkhamiFaculty of Chemistry, Bu-Ali Sina University, Hamedan, 6517838695, Iran. afkhami@basu.ac.ir.ORCID http://orcid.org/0000-0002-3559-2080
Tayebeh MadrakianFaculty of Chemistry, Bu-Ali Sina University, Hamedan, 6517838695, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fluorescence of ZnS quantum dots in colloidal water solution changes very slightly on addition of glutathione (GSH) but is strongly enhanced in the presence of Zn(II) even in concentrations as low as 10 μM. The resulting Zn(II)-enhanced fluorescence is found to be quenched by GSH. In contrast to GSH, cysteine does not cause an effect. Response surface methodology was applied to optimize the experimental parameters. The best data can be obtained at 305/427 nm as excitation/emission wavelengths. These findings were used to design an indirect method for the fluorometric determination of GSH that has a 0.9 μM detection limit and a response that is linear in the 2.0-104.0 μM GSH concentration range. The relative standard deviation at a level of 65 μM of GSH (for n = 5) is 1.9%. Graphical abstract Schematic presentation of the detection strategy for glutathione and the influence of the mediator (Zn

Indexed as

CCD optimizationFluorescence enhancementGSHIndirect detectionMPA-ZnS quantum dotsQuantum efficiencyQuenchingQuenching efficiency

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.