Observational studyEuropean journal of nuclear medicine and molecular imaging2019
The impact of revascularization on myocardial blood flow as assessed by positron emission tomography.
Observational study in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed.
- The impact of fast vs. slow rubidium-82 infusion profile on precision and accuracy of PET myocardial blood flow perfusion metrics using a 1-tissue compartment model.European heart journal. Imaging methods and practice · 2025Article
- Peak myocardial work assessment to detect coronary ischemia during dobutamine stress echocardiography.Frontiers in cardiovascular medicine · 2025Article
- Evaluation of the Usefulness of the Myocardial Flow Reserve Index Using an Anger-Type SPECT/CT System.Annals of nuclear cardiology · 2025Article
- Impact of coronary revascularization on coronary flow capacity measured by transthoracic Doppler echocardiography in patients with chronic coronary syndrome.Scientific reports · 2024Article
- Impact on cardiovascular outcome of coronary revascularization-induced changes in ischemic perfusion defect and myocardial flow reserve.European journal of nuclear medicine and molecular imaging · 2024Article
- Quantitative analysis of myocardial blood flow in surgically revascularized and not revascularized myocardial segments. A pilot PET study.European journal of nuclear medicine and molecular imaging · 2024Article
- Coronary flow capacity and survival prediction after revascularization: physiological basis and clinical implications.European heart journal · 2024Article
- Assessment of resting myocardial blood flow in regions of known transmural scar to confirm accuracy and precision of 3D cardiac positron emission tomography.EJNMMI research · 2023Article
- SPECT measurements of myocardial blood flow and flow reserve: from development to implementation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Myocardial perfusion imaging byEuropean heart journal open · 2023Article
- Indicators of abnormal PET coronary flow capacity in detecting cardiac ischemia.The international journal of cardiovascular imaging · 2023Article
- Development of an approach to extracting coronary arteries and detecting stenosis in invasive coronary angiograms.Journal of medical imaging (Bellingham, Wash.) · 2022Article
- The impact of coronary revascularization on vessel-specific coronary flow capacity and long-term outcomes: a serial [15O]H2O positron emission tomography perfusion imaging study.European heart journal. Cardiovascular Imaging · 2022Article
- Are we good enough in the evaluation of MPI using Rubidium82 with PMT PET/CT? A comparison to SiPM PET/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Quantification of Resting Myocardial Blood Flow Using RubidumAnnals of nuclear cardiology · 2022Article
- PET Stress Testing with Coronary Flow Capacity in the Evaluation of Patients with Coronary Artery Disease and Left Ventricular Dysfunction: Rethinking the Current Paradigm.Current cardiology reports · 2021Review
- Reliability and Reproducibility of Absolute Myocardial Blood Flow: Does It Depend on the PET/CT Technology, the Vasodilator, and/or the Software?Current cardiology reports · 2021Review
- Imaging of coronary flow capacity: is there a role for dynamic CT perfusion imaging?European journal of nuclear medicine and molecular imaging · 2019Article
- The potential for PET-guided revascularization of coronary artery disease.European journal of nuclear medicine and molecular imaging · 2019Article
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Funding
Abstract
purposeRevascularization aims to improve myocardial perfusion. However, changes in regional artery-specific quantitative perfusion after revascularization have not been systematically investigated. It is unclear whether artery-specific thresholds for coronary flow capacity (CFC) and/or relative perfusion predict improved stress perfusion after revascularization. We sought to determine the impact of revascularization based on predefined, artery-specific, severity size thresholds for CFC and/or relative perfusion defects.
methodsFifty patients underwent PET imaging before revascularization and then prospectively within 90 days after revascularization. Changes in regional myocardial blood flow (MBF) were stratified based on baseline perfusion abnormalities, baseline reduced CFC, and whether revascularization was performed in that region.
resultsFollowing angiographic stenosis-directed revascularization, in regions with relative perfusion abnormalities and decreased CFC, stress MBF (sMBF) increased by 0.51 cm
conclusionRevascularization targeted to regions with reduced CFC and relative perfusion abnormalities on baseline PET yielded significant improvements in sMBF. When revascularization was performed in regions without reduced CFC, sMBF did not improve.
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