Evidence map›Paper›PMID 30806731›Full record

ArticleRheumatology international2019

Power-Doppler perfusion phenotype in RA patients is dependent on anti-citrullinated peptide antibody status, not on rheumatoid factor.

O Gadeholt, M Feuchtenberger, T Wech, E C Schwaneck

Abstract read
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In one paragraph

Article in Rheumatology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

O GadeholtDepartment of Rheumatology, Medical Clinic II, University Clinic Würzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany. o.gadeholt@rheuma-wuerzburg.de.ORCID http://orcid.org/0000-0001-6320-4818
M FeuchtenbergerMed I Bayern Ost, Burghausen, Germany.ORCID http://orcid.org/0000-0001-8028-8099
T WechDepartment of Experimental Radiology, University Clinic Würzburg, Würzburg, Germany.ORCID http://orcid.org/0000-0002-2813-7100
E C SchwaneckDepartment of Rheumatology, Medical Clinic II, University Clinic Würzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.ORCID http://orcid.org/0000-0003-1935-2092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is not known whether there are any consistent non-serological differences between seropositive and seronegative rheumatoid arthritis, and if any, whether they depend upon rheumatoid factor (RF), anti-citrullinated peptide antibodies (ACPA), or both. In a pilot study, we showed that the two forms could be differentiated using power-Doppler sonography (PDS), and that the difference is ACPA dependent. This extended study explored whether the previous findings could be confirmed. 103 patients 51 ACPA positive (ACPA +), 52 ACPA negative (ACPA -) with active wrist arthritis were examined using PDS. By means of a temporal image series, pulsatility was evaluated over a 3-5-s period, maximum and minimum perfusion signal were determined using a computer program counting the number of coloured pixels for each frame. Maxima (P

Indexed as

AgedAnti-Citrullinated Protein AntibodiesArthritis, RheumatoidFemaleHumansMaleMiddle AgedPhenotypeRheumatoid FactorUltrasonography, DopplerWrist JointAnti-Citrullinated Protein AntibodiesRheumatoid FactorACPA-negative RAPerfusion patternPower-Doppler sonography

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.