Evidence map›Paper›PMID 30806593›Full record

ArticleGlobal health action2019

Tuberculosis screening among pregnant women attending a tertiary care hospital in Puducherry, South India: is it worth the effort?

Mathavaswami Vijayageetha, Ajay Mv Kumar, Jayalakshmy Ramakrishnan, Sonali Sarkar, Dasari Papa, Kedar Mehta, Noyal M Joseph, Manju Rajaram, Sathish Rajaa, Palanivel Chinnakali

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Mathavaswami Vijayageethaa Department of Preventive and Social Medicine , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Puducherry , India.ORCID 0000-0002-1632-8006
Ajay Mv Kumarb Center for Operational Research , International Union Against Tuberculosis and Lung Disease , Paris , France.ORCID 0000-0003-1011-8531
Jayalakshmy Ramakrishnana Department of Preventive and Social Medicine , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Puducherry , India.
Sonali Sarkara Department of Preventive and Social Medicine , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Puducherry , India.
Dasari Papad Department of Obstetrics and Gynaecology , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Puducherry , India.
Kedar Mehtae Department of Community Medicine , GMERS Medical College , Vadodara , India.ORCID 0000-0003-4374-9495
Noyal M Josephf Department of Microbiology , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Puducherry , India.
Manju Rajaramg Department of Pulmonary Medicine , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Puducherry , India.
Sathish Rajaaa Department of Preventive and Social Medicine , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Puducherry , India.
Palanivel Chinnakalia Department of Preventive and Social Medicine , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Puducherry , India.ORCID 0000-0001-8320-1016
Jawaharlal Institute of Post Graduate Medical Education and Research · INInternational Union Against Tuberculosis and Lung Disease · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe national tuberculosis (TB) programme in India recommends screening all pregnant women for TB, but this is rarely implemented. We carried out systematic TB screening among women attending the antenatal clinic of a tertiary care hospital in Puducherry, South India, during February to April 2018.

objectiveTo assess the number screened and number (proportion) with presumptive and active TB, and understand potential implementation from the healthcare providers' perspective.

methodsWe conducted a mixed-methods study. The quantitative phase was a cross-sectional study including 4203 pregnant women. Data were captured using a structured proforma. Any of the following symptoms constituted 'presumptive TB': any cough, haemoptysis, fever, weight loss, night sweats, neck swellings, joint pains, neck stiffness and disorientation. Those screening positive were referred for investigations and evaluation by a chest physician. The qualitative phase involved seven one-to-one interviews with healthcare providers. Manual thematic analysis was performed to generate themes.

resultsAmong 4203 women (two HIV-positive) screened, 77 (1.8%) had presumptive TB. Cough was the predominant symptom (n = 75). Only 12 women could produce a sputum sample, of whom one (0.02%) was diagnosed with active TB by the Xpert MTB/RIF assay. Challenges cited by healthcare providers were lack of awareness among clients and providers, high case load, lack of dedicated staff, perception that TB screening is a low-yield, low-priority activity and losses in the referral process. Suggested solutions were providing dedicated staff and space for screening, educating women to self-report using posters and videos, and creating a one-stop care provision.

conclusionsThe TB yield among pregnant women was very low, calling into question the value of systematic screening in a low-HIV setting. However, the findings may not be generalizable. Evidence is urgently needed from primary and secondary care facilities. The challenges and solutions identified may help in optimizing the screening process.

Indexed as

Mass ScreeningTertiary Care CentersAdultCross-Sectional StudiesFemaleGuideline AdherenceHIV InfectionsHumansIndiaInterviews as TopicPregnancyPrevalenceQualitative ResearchTuberculosisYoung Adultactive case findingAntenatal womenintensified case findingoperational researchSORT IT

Identifiers

PMID30806593
PMCPMC6394292
OpenAlexW2915717366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.