Trial reportAge and ageing2019
Effect of person-centred care on antipsychotic drug use in nursing homes (EPCentCare): a cluster-randomised controlled trial.
Trial report in Age and ageing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02295462 (Effect of Person-Centred-Care on Antipsychotic Drug Use in Nursing Homes), which is not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Person-Centred-Care on Antipsychotic Drug Use in Nursing Homes: a Cluster-randomised Trial
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Interventions for preventing falls in older people in care facilities.The Cochrane database of systematic reviews · 2025Pooled it
- Interventions to Address Potentially Inappropriate Prescribing for Older Primary Care Patients: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Psychosocial interventions for reducing antipsychotic medication in care home residents.The Cochrane database of systematic reviews · 2023Pooled it
- Trial
- Process evaluation of a tailored intervention to Reduce Inappropriate psychotropic Drug use in nursing home residents with dementia.BMC geriatrics · 2021Trial
- [Health status of older people in long-term inpatient care-a narrative review].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026Review
- Implementing antipsychotic reduction in long-term care: interdisciplinary and lived-experience insights into system-level barriers and facilitators.The Gerontologist · 2026Article
- Barriers and facilitators to implementing strategies for reducing inappropriate antipsychotic use in long-term care: a scoping review.BMC geriatrics · 2026Article
- Proton Pump Inhibitor Prescription in Nursing Home Residents: Prevalence, Appropriateness, and Associated Factors-A Secondary Data Analysis from Three German Regions and the Impact of Guideline Recommendations.Pharmaceuticals (Basel, Switzerland) · 2024Article
- The Impact of Training in Multimodal Communication Skills on Psychotropic Medication Use in Dementia Care.Cureus · 2024Article
- [Safe discontinuation of psychotropic drugs in older people? : New evidence and practical approach].Der Nervenarzt · 2024Review
- Article
- [Health promotion and prevention in nursing homes in the context of the German Prevention Act].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2023Review
- Integrating social support into interventions among the elderly in nursing homes: a scoping review.BMJ open · 2023Article
- [Safe discontinuation of psychotropic drugs in older people? : New evidence and practical approach].Zeitschrift fur Gerontologie und Geriatrie · 2023Review
- Article
- Article
- Contextual factors influencing complex intervention research processes in care homes: a systematic review and framework synthesis.Age and ageing · 2022Article
- Prevalence of oropharyngeal dysphagia in geriatric patients and real-life associations with diseases and drugs.Scientific reports · 2021Article
- Interventions to optimize medication use in nursing homes: a narrative review.European geriatric medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundantipsychotic drugs are regularly prescribed as first-line treatment for neuropsychiatric symptoms in persons with dementia although guidelines clearly prioritise non-pharmacological interventions.
objectivewe investigated a person-centred care approach, which has been successfully evaluated in nursing homes in the UK, and adapted it to German conditions.
designa 2-armed 12-month cluster-randomised controlled trial.
settingnursing homes in East, North and West Germany.
methodsall prescribing physicians from both study arms received medication reviews for individual patients and were offered access to 2 h of continuing medical education. Nursing homes in the intervention group received educational interventions on person-centred care and a continuous supervision programme. Primary outcome: proportion of residents receiving at least one antipsychotic prescription after 12 months of follow-up. Secondary outcomes: quality of life, agitated behaviour, falls and fall-related medical attention, a health economics evaluation and a process evaluation.
resultsthe study was conducted in 37 nursing homes with n = 1,153 residents (intervention group: n = 493; control group: n = 660). The proportion of residents with at least one antipsychotic medication changed after 12 months from 44.6% to 44.8% in the intervention group and from 39.8 to 33.3% in the control group. After 12 months, the difference in the prevalence was 11.4% between the intervention and control groups (95% confidence interval: 0.9-21.9; P = 0.033); odds ratio: 1.621 (95% confidence interval: 1.038-2.532).
conclusionsthe implementation of a proven person-centred care approach adapted to national conditions did not reduce antipsychotic prescriptions in German nursing homes.
trial registrationClinicalTrials.gov NCT02295462.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.