SynthesisThe British journal of psychiatry : the journal of mental science2019
Lung cancer incidence in patients with schizophrenia: meta-analysis.
Synthesis in The British journal of psychiatry : the journal of mental science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Causal effects between personality and psychiatric traits and lung cancer: a bidirectional two-sample Mendelian randomization and bibliometric study.Frontiers in psychiatry · 2024Pooled it
- Concomitant pathologies and their impact on schizophrenia: a narrative overview of current evidence.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Cancer-related mortality among individuals with schizophrenia: systematic review and meta-analysis of cohort studies.BJPsych open · 2026Review
- A multi-level exploration of the genetic basis between lung cancer and schizophrenia.Annals of general psychiatry · 2025Article
- Cancer in Severe Mental Illness Patients: A Retrospective Study.Psycho-oncology · 2025Article
- Ensemble machine learning models for lung cancer incidence risk prediction in the elderly: a retrospective longitudinal study.BMC cancer · 2025Article
- Relationship Between Clozapine and Non-Hematological Malignant Tumors: A Pharmacovigilance Analysis Using the FDA Adverse Event Reporting System Database.Drugs - real world outcomes · 2024Article
- FOXP2 inhibits the aggressiveness of lung cancer cells by blocking TGFβ signaling.Oncology letters · 2024Article
- Genetic prediction of the causal relationship between schizophrenia and tumors: a Mendelian randomized study.Frontiers in oncology · 2024Article
- Association between cumulative exposure periods of flupentixol or any antipsychotics and risk of lung cancer.Communications medicine · 2023Article
- A comprehensive analysis of lung cancer highlighting epidemiological factors and psychiatric comorbidities from the All of Us Research Program.Scientific reports · 2023Article
- The Risk and The Course of Cancer Among People with Severe Mental Illness.Clinical practice and epidemiology in mental health : CP & EMH · 2023Review
- Adenosine, Schizophrenia and Cancer: Does the Purinergic System Offer a Pathway to Treatment?International journal of molecular sciences · 2022Review
- A Comprehensive Survey on the Progress, Process, and Challenges of Lung Cancer Detection and Classification.Journal of healthcare engineering · 2022Review
- Challenges in Treating Cancer Patients With Unstable Psychiatric Disorder.World journal of oncology · 2021Review
- Association between mental disorders and somatic conditions: protocol for an umbrella review.Evidence-based mental health · 2020Article
- The overall and sex- and age-group specific incidence rates of cancer in people with schizophrenia: a population-based cohort study.Epidemiology and psychiatric sciences · 2020Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLung cancer risk factors, like tobacco smoking, are highly prevalent in patients with schizophrenia. Whether these patients have a higher risk of lung cancer remains unknown.
aimsWe aimed to investigate whether patients with schizophrenia have a higher incidence of lung cancer compared with general population, in a meta-analysis.
methodEligible studies were searched from PubMed and EMBASE databases to identify cases of lung cancer in patients with schizophrenia and the general population. This meta-analysis utilised the random-effects model and prediction interval was used to calculate the heterogeneity of these eligible studies. We assessed the quality of evidence with the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.
resultsThere were 12 studies, totalling 496 265 patients, included in this meta-analysis. The data showed that the baseline schizophrenia diagnosis was not associated with any changes in lung cancer incidence in the overall population, with a standardised incidence ratio of 1.11 (95% CI 0.90-1.37; P = 0.31), although there was a significant heterogeneity among these studies (I2 = 94%). Moreover, there was also a substantial between-study variance with wide prediction interval values (0.47-2.64). The data were consistent for both males and females.
conclusionsUp-to-date evidence from epidemiological studies indicates the lack of certainty about the association between schizophrenia diagnosis and lung cancer incidence.
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