ArticleMicrobial biotechnology2019
Omnipresent Maxwell's demons orchestrate information management in living cells.
Article in Microbial biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Article
- A model industrial workhorse: Bacillus subtilis strain 168 and its genome after a quarter of a century.Microbial biotechnology · 2023Review
- Returning to basic principles to develop more effective treatments for central nervous system disorders.Experimental biology and medicine (Maywood, N.J.) · 2022Article
- In vivo, in vitro and in silico: an open space for the development of microbe-based applications of synthetic biology.Microbial biotechnology · 2022Article
- How strand exchange protein function benefits from ATP hydrolysis.Current opinion in genetics & development · 2021Review
- Biomolecular Basis of Cellular Consciousness via Subcellular Nanobrains.International journal of molecular sciences · 2021Review
- Three overlooked key functional classes for building up minimal synthetic cells.Synthetic biology (Oxford, England) · 2021Article
- One-carbon metabolism, folate, zinc and translation.Microbial biotechnology · 2020Article
- Why Nature Chose Potassium.Journal of molecular evolution · 2019Review
- The Alanine World Model for the Development of the Amino Acid Repertoire in Protein Biosynthesis.International journal of molecular sciences · 2019Review
- The Informational Substrate of Chemical Evolution: Implications for Abiogenesis.Life (Basel, Switzerland) · 2019Article
- Towards a General Definition of Life.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2019Article
- Omnipresent Maxwell's demons orchestrate information management in living cells.Microbial biotechnology · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of synthetic biology calls for accurate understanding of the critical functions that allow construction and operation of a living cell. Besides coding for ubiquitous structures, minimal genomes encode a wealth of functions that dissipate energy in an unanticipated way. Analysis of these functions shows that they are meant to manage information under conditions when discrimination of substrates in a noisy background is preferred over a simple recognition process. We show here that many of these functions, including transporters and the ribosome construction machinery, behave as would behave a material implementation of the information-managing agent theorized by Maxwell almost 150 years ago and commonly known as Maxwell's demon (MxD). A core gene set encoding these functions belongs to the minimal genome required to allow the construction of an autonomous cell. These MxDs allow the cell to perform computations in an energy-efficient way that is vastly better than our contemporary computers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.