Evidence map›Paper›PMID 30805967›Full record

ArticleAngewandte Chemie (International ed. in English)2019

A Polymer Coating Transfer Enrichment Method for Direct Mass Spectrometry Analysis of Lipids in Biofluid Samples.

Wenpeng Zhang, Spencer Chiang, Zishuai Li, Qinhua Chen, Yu Xia, Zheng Ouyang

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Materials today. Bio · 2022
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenpeng ZhangState Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing, 100084, China.ORCID 0000-0002-7018-930X
Spencer ChiangState Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing, 100084, China.
Zishuai LiState Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing, 100084, China.
Qinhua ChenAffiliated Dongfeng Hospital, Hubei University of Medicine, Shiyan, 442000, China.
Yu XiaDepartment of Chemistry, Tsinghua University, Beijing, 100084, China.ORCID 0000-0001-8694-9900
Zheng OuyangState Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing, 100084, China.ORCID 0000-0002-7932-0933

Funding

Novel approaches for quantitative assessment of adherenceR01AI122298 · NIAID · UNIVERSITY OF COLORADO DENVER · PI ANDERSON, PETER L. · 2016 to 2020
$3.4M
Quantification of Circulating Antigens for Pediatric TB Diagnosis andTreatment MonitoringR01AI122932 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI HU, TONY Y. · 2016 to 2019
$1.8M
Mass spectrometry method with C=C location specificity for qualitative and quantitative lipid analysisR01GM118484 · NIGMS · PURDUE UNIVERSITY · PI MCLUCKEY, SCOTT A · 2016 to 2020
$1.6M
Development of a Miniature Mass Spectromtry System for Point-of-Care ApplicationsR44GM119584 · NIGMS · PURSPEC TECHNOLOGIES, INC. · PI REN, YUE · 2017 to 2018
$1.3M
National Natural Science Foundation of China 21627807National Natural Science Foundation of China 21874081NIAID NIH HHS R01 AI122298NIAID NIH HHS R01 AI122932NIGMS NIH HHS R01 GM118484NIGMS NIH HHS R44 GM119584
6 · The paper itself

Abstract

A porous polymer coating transfer enrichment method is developed for the direct mass spectrometry (MS) analysis of lipids. The enrichment is fast (ca. 1 min) and enables the profiling and quantitation of lipids in small-volume biofluid samples. Coupled with a photochemical Paternò-Büchi reaction, this method enables the fast determination of lipid structure at the C=C location level and point-of-care lipid biomarker analysis.

Indexed as

LipidsMolecular StructurePolymersSpectrometry, Mass, Electrospray IonizationLipidsPolymersanalyte enrichmentbiofluidslipid isomersmass spectrometrypolymer coatings

Identifiers

PMID30805967
PMCPMC6541494

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.