SynthesisClinical autonomic research : official journal of the Clinical Autonomic Research Society2019
Epidemiology and pathophysiology of autonomic seizures: a systematic review.
Synthesis in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
- Copeptin as a predictor of seizure diagnosis and seizure type in emergency department patients.BMC neurology · 2026Observational
- HRV features as potential biomarkers for auxiliary diagnosis in epilepsy.Scientific reports · 2026Article
- Quantitative EEG and dysautonomia in patients with temporal lobe epilepsy.Acta epileptologica · 2026Article
- Owner reported prevalence of autonomic signs in epileptic dogs.Frontiers in veterinary science · 2026Article
- Validity of Empatica E4 Wristband for Detection of Autonomic Dysfunction Compared to Established Laboratory Testing.Diagnostics (Basel, Switzerland) · 2025Article
- Autonomic biosignals, seizure detection, and forecasting.Epilepsia · 2025Review
- Change of heart rate variability in children and adolescent with drug resistant epilepsy.Scientific reports · 2025Article
- Seizure Detection Devices.Journal of clinical medicine · 2025Review
- Article
- Epilepsy in rural South Africa: Patient experiences and healthcare challenges.Epilepsia open · 2024Article
- Peri-ictal Water Drinking in an Omani Patient with Bilateral Mesial Temporal Sclerosis.Sultan Qaboos University medical journal · 2024Article
- The Reciprocal Relationship between Sleep and Epilepsy.Journal of personalized medicine · 2024Review
- The Metabolic Role of Ketogenic Diets in Treating Epilepsy.Nutrients · 2022Review
- Gastrointestinal and Autonomic Symptoms-How to Improve the Diagnostic Process in Panayiotopoulos Syndrome?Children (Basel, Switzerland) · 2022Review
- A flurothyl-induced seizure does not disrupt hippocampal memory reconsolidation in C57BL/6 J mice.Epilepsy research · 2022Article
- Article
- Autonomic manifestations of epilepsy: emerging pathways to sudden death?Nature reviews. Neurology · 2021Review
- A novel compound heterozygous EPM2A mutation in a Chinese boy with Lafora disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- The autonomic signatures of epilepsy: diagnostic clues and novel treatment avenues.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo review the epidemiology and pathophysiology of autonomic symptoms and signs during epileptic seizures.
methodsWe performed a systematic literature search on the following autonomic symptoms and signs during epileptic seizures: cardiovascular changes, respiratory manifestations, gastrointestinal symptoms, cutaneous manifestations, sexual and genital manifestations, and urinary symptoms.
resultsAutonomic symptoms and signs can represent the predominant symptom at the onset of a focal seizure, which would then lead to the seizure being classified as a focal onset autonomic seizure. Conversely, clinically relevant autonomic symptoms and signs frequently accompany seizures of focal, generalized, and/or unknown onset, but the seizure is regardless classified according to other, more relevant features. Autonomic symptoms and signs do not represent mere reactions to motor activity or other behavioral seizure manifestations, but rather they are generated by epileptic discharges affecting the central autonomic network. We have reviewed the localizing and lateralizing information currently available on the seizure onset zone and on seizure propagation pathways as provided by systematic analysis of specific autonomic seizure symptoms and signs. We present data on how autonomic seizure symptoms and signs are useful for gaining a better understanding of the anatomical and functional organization of the central autonomic network. Finally, we discuss the differential diagnosis of focal autonomic seizures with autonomic symptoms and signs representing the sole seizure manifestation versus various non-epileptic conditions.
conclusionsAutonomic seizure symptoms and signs are relevant in clinical epileptology and open a unique window on the functional organization and pathophysiology of the central autonomic network.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.