Evidence map›Paper›PMID 30805782›Full record

ArticleSurgical endoscopy2019

Long-term outcomes after non-curative endoscopic submucosal dissection for early gastric cancer according to hospital volumes in Japan: a multicenter propensity-matched analysis.

Osamu Dohi, Waku Hatta, Takuji Gotoda, Yuji Naito, Tsuneo Oyama, Noboru Kawata, Akiko Takahashi, Shiro Oka, Shu Hoteya, Masahiro Nakagawa and 13 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Outcomes of endoscopic submucosal dissection for locally recurrent early gastric cancer after endoscopic resection: analysis of a multicenter prospective cohort study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Observational
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Osamu DohiDepartment of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Waku HattaDepartment of Gastroenterology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan. waku-style@festa.ocn.ne.jp.
Takuji GotodaDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.
Yuji NaitoDepartment of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tsuneo OyamaDivision of Endoscopy, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Noboru KawataDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Akiko TakahashiDivision of Endoscopy, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Shiro OkaDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Shu HoteyaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Masahiro NakagawaDepartment of Endoscopy, Hiroshima City Hospital, Hiroshima, Japan.
Masaaki HiranoDepartment of Internal Medicine, Niigata Prefectural Central Hospital, Joetsu, Japan.
Mitsuru EsakiDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.
Mitsuru MatsudaDepartment of Internal Medicine, Toyama Prefectural Central Hospital, Toyama, Japan.
Ken OhnitaDepartment of Gastroenterology and Hepatology, Nagasaki University Hospital, Nagasaki, Japan.
Ryo ShimodaDepartment of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Saga, Japan.
Motoyuki YoshidaDepartment of Gastroenterology and Endocrinology and Metabolism, Nara Medical University, Nara, Japan.
Jun TakadaDepartment of Gastroenterology, Gifu University Graduate School of Medicine, Gifu, Japan.
Keiko TanakaDepartment of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.
Shinya YamadaDepartment of Gastroenterology and Hepatology, Japanese Red Cross Society Kyoto Daiichi Hospital, Kyoto, Japan.
Tsuyotoshi TsujiDepartment of Gastroenterology, Akita City Hospital, Akita, Japan.
Hirotaka ItoDepartment of Gastroenterology, Osaki Citizen Hospital, Osaki, Japan.
Hiroyuki AoyagiDepartment of Gastroenterology, Fukui Prefectural Hospital, Fukui, Japan.
Tooru ShimosegawaDepartment of Gastroenterology, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a lack of data regarding the long-term outcomes of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) without curative resection, and the relationship of these outcomes with hospital volumes remains unclear. This study evaluated long-term outcomes of patients who underwent ESD for EGC without curative resection according to hospital volumes in Japan.

methodsThis multicenter retrospective study evaluated 1,969 patients who did not meet the criteria of the Japanese Gastric Cancer Association for curative resection between January 2000 and August 2011. Hospitals were classified according to the annual number of ESD procedures: low- and medium-volume group (LMVG), high-volume group (HVG), and very high-volume group (VHVG). Clinicopathological features, overall survival (OS), disease-specific survival (DSS), and recurrence-free survival (RFS) were compared across groups after a generalized propensity score matching analysis.

resultsIn 495 pairs of generalized propensity score-matched patients, the 5-year OS, DSS, and RFS rates were 81.5%, 97.9%, and 97.6% for LMVG; 86.9%, 98.2%, and 97.0% for HVG; and 85.4%, 98.5%, and 97.6% for VHVG, respectively. The 5-year DSS and RFS rates did not significantly differ among the three groups. However, 5-year OS was significantly worse in the LMVG than in the HVG and VHVG (P < 0.001 and P = 0.008, respectively).

conclusionsDSS and RFS in patients with EGC who did not meet the criteria for curative resection did not differ across hospital volumes in Japan. Even in cases in which ESD for EGC involved non-curative resection, the procedure is feasible across Japanese hospitals with different volumes.

Indexed as

Early Detection of CancerEndoscopic Mucosal ResectionHospitalsHumansJapanPropensity ScoreRetrospective StudiesStomach NeoplasmsTreatment OutcomeEarly gastric cancerEndoscopic submucosal dissectionHospital volumeLong-term outcomePropensity score matching

Identifiers

PMID30805782

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.