Evidence map›Paper›PMID 30805702›Full record

ArticleEuropean radiology2019

Real-time MRI for the dynamic assessment of fundoplication failure in patients with gastroesophageal reflux disease.

Ali Seif Amir Hosseini, Johannes Uhlig, Ulrike Streit, Dirk Voit, Annemarie Uhlig, Volker Ellenrieder, Michael Ghadimi, Thilo Sprenger, Alexander Beham, Martin Uecker and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Real-Time Magnetic Resonance Imaging.Journal of magnetic resonance imaging : JMRI · 2022
    Review
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ali Seif Amir HosseiniDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany. ali.seif@med.uni-goettingen.de.
Johannes UhligDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany.
Ulrike StreitDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany.
Dirk VoitBiomedical NMR, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
Annemarie UhligDepartment of Urology, University Medical Center Göttingen, Göttingen, Germany.
Volker EllenriederDepartment of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany.
Michael GhadimiDepartment of General, Visceral, and Paediatric Surgery, University Medical Center, Göttingen, Germany.
Thilo SprengerDepartment of General, Visceral, and Paediatric Surgery, University Medical Center, Göttingen, Germany.
Alexander BehamDepartment of General, Visceral, and Paediatric Surgery, University Medical Center, Göttingen, Germany.
Martin UeckerDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany.
Jens FrahmBiomedical NMR, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
Joachim LotzDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany.
Lorenz BiggemannDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany.
Universitätsmedizin Göttingen · DEGerman Centre for Cardiovascular Research · DEMax Planck Institute for Biophysical Chemistry · DEUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the diagnostic potential of dynamic real-time MRI for fundoplication failure in patients with persistent or recurrent GERD-like (gastroesophageal reflux disease) complaints. MATERIAL AND

methodsTwenty-two consecutive patients (male n = 11; female n = 11; median age 59 years) with recurrent or persistent GERD-like symptom after fundoplication were enrolled between 2015 and 2017. Median duration of GERD-like symptoms was 21 months. Real-time MRI (3 Tesla) was performed at 40 ms temporal resolution using undersampled radial fast low-angle shot acquisitions with nonlinear inverse image reconstruction. MRI movies dynamically visualized bolus transit of pineapple juice through the gastroesophageal junction, position of the fundoplication wrap and recurring hernia or reflux during Valsalva maneuver. MRI results were compared to endoscopic findings.

resultsReal-time MRI was successfully completed in all patients without adverse events (average examination time 15 min). Morphological correlates for GERD-like symptoms were evident in 20 patients (90.1%) with gastric reflux in 19 cases. Nine patients (40.1%) had wrap disruption and recurrent gastric hernia. Wrap migration or telescoping hernia was detected in nine patients (40.1%). One patient presented with continued reflux despite intact fundoplication wrap. Esophageal dysmotility with delayed bolus passage was observed in one case. On endoscopy, gastric hernia or wrap disruption was diagnosed in seven cases, and esophagitis or Barret's metaplasia in nine cases.

conclusionReal-time MRI is a fast and safe modality for dynamic imaging after fundoplication, without radiation exposure or administration of gadolinium-based contrast media. In a relevant number of cases, real-time MRI reveals correlates for GERD-like symptoms. KEY POINTS: • Real-time MRI reliably visualizes the gastroesophageal junction after fundoplication surgery. • Patients with recurring GERD-like symptoms have a high rate of morphological failure patterns that can be identified by real-time MRI. • Dynamic assessment of gastroesophageal junction by real-time MRI is a perspective diagnostic tool for detection of fundoplication failure.

Indexed as

FundoplicationAdolescentAdultAgedEsophagogastric JunctionFemaleGastroesophageal RefluxHumansMagnetic Resonance ImagingMaleMiddle AgedRecurrenceReproducibility of ResultsTreatment FailureTreatment OutcomeYoung AdultFundoplicationGastroesophageal reflux disease (GERD)Magnetic resonance imaging

Identifiers

PMID30805702
OpenAlexW2917297974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.