ReviewWorld journal of urology2019
What is a disease? What is the disease clinical benign prostatic hyperplasia (BPH)?
Review in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04802252 (A Diagnostic Study of Abnormal Acoustic Waves in Modern Pulse in Benign Prostatic Hyperplasia), which is not on this map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Diagnostic Study of Abnormal Acoustic Waves in Modern Pulse in Benign Prostatic Hyperplasia
Who cites it
55 citing papers in PubMed.
- Impact of laser power settings on sexual and urinary outcomes in holmium laser enucleation of the prostate: a multicenter randomized controlled trial.Lasers in medical science · 2025Trial
- Comparative study of low-power versus high-power holmium laser enucleation of the prostate for large volume benign prostatic hyperplasia.Lasers in medical science · 2025Trial
- Technological innovation of HoLEP: a multicenter, randomized, controlled study for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia.World journal of urology · 2025Trial
- Comparative analysis of low-power versus high-power holmium laser enucleation of the prostate for symptomatic small-volume benign prostatic hyperplasia: a prospective randomized controlled trial.The Journal of international medical research · 2024Trial
- Outcomes of thulium prostatectomy with "Oyster technique" versus transurethral prostatectomy (TURP): a randomized control trial.World journal of urology · 2023Trial
- Biomechanical regulation of bladder injury and repair.Nature reviews. Urology · 2026Review
- Causal links of 233 metabolic markers to benign prostatic hyperplasia: Mendelian randomization and RNA-sequencing insights.Journal of the Chinese Medical Association : JCMA · 2026Article
- Gut microbes and benign prostatic hyperplasia: the role of dysbiosis.Frontiers in urology · 2026Review
- Observational
- Review
- Clinical comparison of TURP, PVP and holep for small volume BPH.Scientific reports · 2025Article
- Paeonol Ameliorates Benign Prostatic Hyperplasia via Suppressing Proliferation and NF-κB-In Silico and Experimental Studies.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Comparison of the efficacy and safety of holmium laser enucleation of the prostate and prostate artery embolization: Short-term follow-up results.Prostate international · 2025Article
- Urinary Inflammatory and Oxidative Stress Biomarkers as Indicators for the Clinical Management of Benign Prostatic Hyperplasia.International journal of molecular sciences · 2025Article
- A comparison between thulium fiber laser enucleation of the prostate and robot-assisted simple prostatectomy in the surgical management of large benign prostatic hyperplasia.Asian journal of urology · 2025Article
- Association between dietary calcium intake and benign prostatic hyperplasia: a population-based result from NHANES 2003 to 2008.Translational andrology and urology · 2025Article
- Clinical Application Effect of Postoperative Nursing Intervention on Patients Undergoing Transurethral Prostatectomy: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2025Review
- Transcutaneous tibial nerve stimulation combined mirabegron therapy significantly improves benign prostatic hyperplasia and overactive bladder: a prospective randomized controlled trial.American journal of translational research · 2025Article
- The pathogenesis of benign prostatic hyperplasia and the roles of Prdx3, oxidative stress, pyroptosis and autophagy:a review.Frontiers in oncology · 2025Review
- Clinical-radiomics combination model for predicting the short-term efficacy of bipolar transurethral enucleation of the prostate in patients with benign prostatic hyperplasia.Current urology · 2025Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThough clinical benign prostatic hyperplasia (BPH) is a common disease worldwide, there is still much confusion in the literature and the many clinical guidelines as to its definition. Often the disease is associated with lower urinary tract symptoms (LUTS) and managed according to only symptoms. This leads to undertreatment in some patients with severe bladder outlet obstruction (BOO) with no symptoms, and overtreatment in patients with LUTS but no clinical BPH. DEFINITION OF A DISEASE: Fundamentally, a disease can be defined as an abnormal structure or function or a condition which may cause harm to the organism. DEFINITION OF CLINICAL BPH: Thus, clinical BPH can be defined as prostate adenoma/adenomata, causing a varying degree of BOO, which may eventually cause harm to the patients. With this definition, we are then able to differentiate the disease clinical BPH from the many other less common causes of LUTS, and then treat it according to its severity. DIAGNOSING CLINICAL BPH: Clinical BPH can be diagnosed with non-invasive ultrasound in the clinic, grading it according to the shape (intravesical prostatic protrusion) and size of the prostate. CLINICAL SIGNIFICANCE: Treatment can then be planned according to the disease severity using our staging system that classifies severity according to the presence or absence of significant obstruction and bothersomeness of symptoms.
conclusionThis would lead to better individualised and cost-effective management of the disease clinical BPH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.