Evidence map›Paper›PMID 30805568›Full record

ArticleJournal of the Endocrine Society2019

Relationship Between Vitamin D Status From Childhood to Early Adulthood With Body Composition in Young Australian Adults.

Kun Zhu, Wendy H Oddy, Patrick Holt, Wendy Chan She Ping-Delfos, Joanne McVeigh, Leon Straker, Trevor A Mori, Stephen Lye, Craig Pennell, John P Walsh

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Kun ZhuDepartment of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.ORCID 0000-0002-8723-7574
Wendy H OddyMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Patrick HoltTelethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia.
Wendy Chan She Ping-DelfosGeneral Practice and Primary Health Care Research Unit, School of Medicine (Fremantle), University of Notre Dame, Perth, Western Australia, Australia.
Joanne McVeighSchool of Occupational Therapy and Social Work, Curtin University, Perth, Western Australia, Australia.
Leon StrakerSchool of Physiotherapy and Exercise Science, Curtin University, Perth, Western Australia, Australia.
Trevor A MoriMedical School, University of Western Australia, Perth, Western Australia, Australia.
Stephen LyeSamuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Craig PennellSchool of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia.
John P WalshDepartment of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.ORCID 0000-0002-1766-2612
The University of Western Australia · AUCurtin University · AUMount Sinai Hospital · CAThe Kids Research Institute Australia · AUThe University of Notre Dame Australia · AUUniversity of Tasmania · AUUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextVitamin D plays a role in the differentiation and metabolism of skeletal muscle and, possibly, adipose tissue; however, the relationship between vitamin D status during growth and body composition in early adulthood is unclear.

objectiveWe examined associations between vitamin D status in childhood, adolescence, and early adulthood with body composition at age 20 years. DESIGN SETTING

participantsWe studied 821 offspring (385 females) of the Western Australian Pregnancy Cohort Study who had ≥3 serum 25-hydroxyvitamin D [25(OH)D] at age 6, 14, 17, and 20 years and body composition assessed at age 20 using dual-energy x-ray absorptiometry. The participants were grouped into four vitamin D status trajectories: consistently lower, decreasing, increasing, and consistently higher.

resultsThe mean serum 25(OH)D at the study visits was 72.7 to 86.8 nmol/L. In males, serum 25(OH)D at 17 and 20 years was positively associated with lean body mass (LBM), and 25(OH)D at age 20 correlated negatively with fat body mass (FBM). Males with a consistently higher 25(OH)D trajectory had a 2.3- to 3.7-kg greater LBM and 4.1- to 6.0-kg lower FBM at 20 years compared with those with consistently lower or decreasing trajectories (

conclusionsIn the present predominantly white, relatively vitamin D-replete cohort, a higher vitamin D status trajectory from childhood to early adulthood was associated with a greater LBM in males and lower FBM in both sexes at age 20.

Indexed as

25-hydroxyvitamin Dbody compositionfat body masslean body massRaine studyyoung adults

Identifiers

PMID30805568
PMCPMC6382407
OpenAlexW2914377367

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.